CAS 479-41-4

Indirubin

Description:

Indirubin is a chemical compound known for its role as a natural dye and its potential therapeutic applications. It is a member of the indole family and is characterized by its deep blue to purple color, which is attributed to its conjugated double bond system. Indirubin is primarily derived from the indigo plant and is often associated with traditional Chinese medicine, where it has been studied for its anti-inflammatory and anti-cancer properties. The compound exhibits a complex structure, featuring both indole and isoindole moieties, which contribute to its biological activity. Indirubin has been shown to inhibit certain kinases, making it a subject of interest in cancer research. Additionally, it is soluble in organic solvents but has limited solubility in water. Its stability and reactivity can vary depending on environmental conditions, such as pH and temperature. Overall, indirubin's unique properties and potential health benefits make it a significant compound in both chemistry and pharmacology.

Formula: C₁₆H₁₀N₂O₂

InChI: InChI=1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,17H,(H,18,20)

InChI key: InChIKey=CRDNMYFJWFXOCH-UHFFFAOYSA-N

SMILES: O=C1C(C=2C(N1)=CC=CC2)=C3NC=4C(C3=O)=CC=CC4

Synonyms:

• (2Z)-2,3'-biindole-2',3(1H,1'H)-dione
• 2,3'-biindole-2',3(1H,1'H)-dione
• 2-(2-Oxo-1H-Indol-3-Ylidene)-1H-Indol-3-One
• 2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-
• 3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one
• Couroupitine B
• Indigo red
• Indigopurpurin
• NSC 105327
• [Δ^2,3′-Biindoline]-2′,3-dione
• [Δ2,3′-Biindoline]-2′,3-dione
• Indirubin

Indirubin

CAS: 479-41-4

Formula: C₁₆H₁₀N₂O₂

Purity: >97.0%(HPLC)

Color and Shape: Red to Dark red to Dark purple powder to crystal

Molecular weight: 262.27

Ref: 3B-I0868

2H-Indol-2-one,3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-

CAS: 479-41-4

Formula: C₁₆H₁₀N₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 262.2628

Ref: IN-DA00350S

Indirubin

CAS: 479-41-4

Indirubin

Purity: 98%

Molecular weight: 262.26g/mol

Ref: 54-OR1026319

Indirubin

CAS: 479-41-4

Indirubin

Purity: ≥95%

Molecular weight: 262.26g/mol

Ref: 54-BUP15431

Indirubin

CAS: 479-41-4

Formula: C₁₆H₁₀N₂O₂

Purity: ≥ 97.0%

Color and Shape: Red to purple powder

Molecular weight: 262.26

Ref: 7W-GP2692

Indirubin

CAS: 479-41-4

Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.

Formula: C₁₆H₁₀N₂O₂

Purity: 97.21% - 99.74%

Color and Shape: Reddish-Violet Powder

Molecular weight: 262.26

Ref: TM-T6169

Indirubin

CAS: 479-41-4

Natural alkaloid

Formula: C₁₆H₁₀N₂O₂

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 262.27

Ref: 5G-89716

Indigopurpurin

Controlled Product

CAS: 479-41-4

Applications Indigopurpurin is a purple 3,2-bisindole derivative and was shown to exhibit inhibitory allergic contact dermatitis via regulating T helper (Th)-mediated immune system in DNCB-induced model. A possible glycogen synthase kinase-3 (GSK-3) inhibitor the active component of a traditional Congolese antiepilepsy treatment.
References Kim, M.H., et al.: J. Ethnopharmacol., 145, 214 (2013); Tahtouh, T., et al.: J. Med. Chem., 55, 9312 (2012); Hsieh, W.L., et al.: J. Dermatol. Sci., 67, 140 (2012); Chem. and Eng. News page 6 Nov. 10 (2018)

Formula: C₁₆H₁₀N₂O₂

Color and Shape: Neat

Molecular weight: 262.26

Ref: TR-I521350

Indirubin - Bio-X ™

CAS: 479-41-4

Indirubin is a chemical compound that belongs to the indole family. It has been studied for its anti-inflammatory and antipyretic properties. Research suggests that Indirubin can inhibit certain kinases displaying antineoplastic properties.

Formula: C₁₆H₁₀N₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 262.26 g/mol

Ref: 3D-BI164578

Indirubin

CAS: 479-41-4

Phosphorylase kinase inhibitor

Formula: C₁₆H₁₀N₂O₂

Purity: Min. 95%

Color and Shape: Purple Powder

Molecular weight: 262.26 g/mol

Ref: 3D-FI65043

Indigopurpurin-d4

Controlled Product

CAS: 479-41-4

Formula: C₁₆D₄H₆N₂O₂

Color and Shape: Neat

Molecular weight: 266.288

Ref: TR-I521352