CAS 479-50-5

Lucanthone

Description:

Lucanthone is a chemical compound with the CAS number 479-50-5, primarily recognized for its use in medicinal chemistry. It is classified as an antiprotozoal agent, historically investigated for its efficacy against schistosomiasis, a disease caused by parasitic worms. Lucanthone exhibits a complex molecular structure, which contributes to its biological activity. The compound is characterized by its ability to interact with nucleic acids, leading to potential cytotoxic effects on the parasites. In terms of solubility, Lucanthone is typically soluble in organic solvents, which is a common trait for many pharmaceutical compounds. Its pharmacological profile includes mechanisms that may involve inhibition of DNA synthesis, making it a subject of interest in both therapeutic and research contexts. However, like many compounds, it may also exhibit side effects and toxicity, necessitating careful consideration in its application. Overall, Lucanthone represents a significant example of the intersection between organic chemistry and pharmacology, highlighting the importance of chemical compounds in addressing infectious diseases.

Formula: C₂₀H₂₄N₂OS

InChI: InChI=1S/C20H24N2OS/c1-4-22(5-2)13-12-21-16-11-10-14(3)20-18(16)19(23)15-8-6-7-9-17(15)24-20/h6-11,21H,4-5,12-13H2,1-3H3

InChI key: InChIKey=FBQPGGIHOFZRGH-UHFFFAOYSA-N

SMILES: N(CCN(CC)CC)C1=C2C(SC=3C(C2=O)=CC=CC3)=C(C)C=C1

Synonyms:

• 1-(2-Diethylaminoethylamino)-4-methylthiaxanthen-9-one
• 1-[[2-(Diethylamino)ethyl]amino]-4-methyl-9H-thioxanthen-9-one
• Lucanthon
• Lucanthone
• Lucatona
• NSC 20530
• Thioxanthen-9-one, 1-[[2-(diethylamino)ethyl]amino]-4-methyl-
• 9H-Thioxanthen-9-one, 1-[[2-(diethylamino)ethyl]amino]-4-methyl-

1-((2-(Diethylamino)ethyl)amino)-4-methyl-9H-thioxanthen-9-one , Lucanthone

CAS: 479-50-5

Formula: C₂₀H₂₄N₂OS

Purity: 95%

Color and Shape: Solid

Molecular weight: 340.4824

Ref: IN-DA00DJXZ

1-((2-(Diethylamino)Ethyl)Amino)-4-Methyl-9H-Thioxanthen-9-One

CAS: 479-50-5

1-((2-(Diethylamino)Ethyl)Amino)-4-Methyl-9H-Thioxanthen-9-One

Purity: 99+%

Molecular weight: 340.48g/mol

Ref: 54-OR1023951

Lucanthone

CAS: 479-50-5

Lucanthone

Purity: ≥98%

Molecular weight: 340.48g/mol

Ref: 54-BUP04288

Lucanthone

CAS: 479-50-5

Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).

Formula: C₂₀H₂₄N₂OS

Purity: 99.92%

Color and Shape: Yellow Crystals From Alcohol Solid

Molecular weight: 340.48

Ref: TM-T4569

Lucanthone

CAS: 479-50-5

Lucanthone is an intramolecular hydrogen-transfer compound that is synthesized from the amino acid cysteine. It has been used in biological studies for its ability to inhibit the growth of cancer cells, and may be useful in radiation therapy. Lucanthone has been shown to have a cytotoxic effect on cancer cells by inhibiting cell proliferation and inducing apoptosis. This compound also inhibits autophagy, which is the process of degrading proteins and organelles. Lucanthone has also been shown to decrease cellular viability in wild-type strains of bacteria such as E. coli, but not mutant strains that lack lucanthone reductase activity. This suggests that lucanthone is an inhibitor of physiological function in mammalian tissues, but not bacterial cell functions.

Formula: C₂₀H₂₄N₂OS

Purity: Min. 95%

Molecular weight: 340.48 g/mol

Ref: 3D-FL161255