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CAS 479064-92-1

:

(R)-Fmoc-4-chlorophenyl-β-Phe-OH

Description:
(R)-Fmoc-4-chlorophenyl-β-Phe-OH is a chemical compound commonly used in peptide synthesis and drug development. It features a phenylalanine derivative with a 4-chlorophenyl group and a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during peptide synthesis. The Fmoc group is known for its stability under basic conditions and can be easily removed under mild acidic conditions, making it advantageous in synthetic chemistry. The presence of the β-phenylalanine structure contributes to the compound's potential biological activity, as it can influence the conformation and interactions of peptides. This compound is typically utilized in research settings, particularly in the development of peptide-based therapeutics and in studies related to protein structure and function. Its specific stereochemistry, indicated by the (R) configuration, plays a significant role in its biological properties and interactions. Overall, (R)-Fmoc-4-chlorophenyl-β-Phe-OH is a valuable tool in the field of medicinal chemistry and peptide synthesis.
Formula:C24H20ClNO4
InChI:InChI=1/C24H20ClNO4/c25-16-11-9-15(10-12-16)22(13-23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)/t22-/m1/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=N[C@H](CC(=O)O)c1ccc(cc1)Cl)O
Synonyms:
  • Fmoc-3-R-4-Chlorophenylalanine
  • Fmoc-(R)-3-Amino-3-(4-chlorophenyl)-propionic acid
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