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CAS 479064-99-8

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Fmoc-L-3-Amino-3-(4-methylphenyl)-propionic acid

Description:
Fmoc-L-3-Amino-3-(4-methylphenyl)-propionic acid is a synthetic amino acid derivative commonly used in peptide synthesis and research. It features a fluorenylmethoxycarbonyl (Fmoc) protective group, which is widely utilized in solid-phase peptide synthesis due to its stability and ease of removal under mild conditions. The compound contains a chiral center, making it an L-amino acid, and its structure includes a 3-amino group and a 4-methylphenyl side chain, contributing to its unique properties. This amino acid is characterized by its ability to participate in peptide bond formation, making it valuable in the development of peptides with specific biological activities. Its solubility in organic solvents and moderate solubility in water allows for versatility in various chemical reactions. Additionally, the presence of the aromatic side chain can influence the hydrophobicity and overall stability of peptides synthesized with this amino acid. Overall, Fmoc-L-3-Amino-3-(4-methylphenyl)-propionic acid is an important building block in the field of medicinal chemistry and peptide design.
Formula:C25H23NO4
InChI:InChI=1/C25H23NO4/c1-16-10-12-17(13-11-16)23(14-24(27)28)26-25(29)30-15-22-20-8-4-2-6-18(20)19-7-3-5-9-21(19)22/h2-13,22-23H,14-15H2,1H3,(H,26,29)(H,27,28)/t23-/m0/s1
SMILES:Cc1ccc(cc1)[C@H](CC(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12
Synonyms:
  • Fmoc-3-S-4-Methylphenylalanine
  • Fmoc-(S)-3-Amino-3-(4-methyl-phenyl)propionic acid
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