CAS 479073-79-5
:Thiosildenafil
Description:
Thiosildenafil is a synthetic compound that belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors, which are primarily used in the treatment of erectile dysfunction. It is structurally related to sildenafil, the active ingredient in Viagra, but features a thioether group that distinguishes it from its parent compound. Thiosildenafil works by enhancing the effects of nitric oxide, leading to increased blood flow to the penis during sexual stimulation. This mechanism involves the inhibition of PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP), a molecule that promotes vasodilation. The compound is characterized by its ability to improve erectile function and may have a similar side effect profile to other PDE5 inhibitors, including headaches, flushing, and potential cardiovascular effects. As with any pharmaceutical, it is essential to use thiosildenafil under medical supervision to ensure safety and efficacy, particularly in individuals with pre-existing health conditions or those taking other medications. Research into its pharmacokinetics and long-term effects is ongoing to better understand its therapeutic potential.
Formula:C22H30N6O3S2
InChI:InChI=1S/C22H30N6O3S2/c1-5-7-17-19-20(27(4)25-17)22(32)24-21(23-19)16-14-15(8-9-18(16)31-6-2)33(29,30)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,32)
InChI key:InChIKey=LJUBVCQVNMLSTQ-UHFFFAOYSA-N
SMILES:O(CC)C1=C(C=C(S(=O)(=O)N2CCN(C)CC2)C=C1)C=3NC4=C(C(=S)N3)N(C)N=C4CCC
Synonyms:- Piperazine, 1-[[3-(4,7-dihydro-1-methyl-3-propyl-7-thioxo-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl-
- 5-[2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidine-7-thione
- 7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-
- Thiosildenafil
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Found 10 products.
Thiosildenafil
CAS:<p>Applications An analog of Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.<br>References DeBono, R., et al.: Pharm. Technol., 26, 72 (2002), Blok-Tip, L., et al.: Food Addit. Contam., 21, 737 (2004), Liang, Q., et al.: J. Pharm. Biomed. Anal., 40, 305 (2006),<br></p>Formula:C22H30N6O3S2Color and Shape:Beige SolidMolecular weight:490.64Thiosildenafil
CAS:<p>Thiosildenafil is a pharmaceutical drug that belongs to the class of phosphodiesterase type-5 inhibitors. It has been shown to have an increased effect on erectile dysfunction (ED) in patients with diabetes. Thiosildenafil inhibits the enzyme phosphodiesterase type-5, which is responsible for breaking down cGMP, a molecule responsible for relaxation of smooth muscles and blood vessels in the penis. This inhibition leads to an increase in cGMP levels and therefore an increase in penile blood flow and arterial inflow, resulting in improved erectile function. Thiosildenafil also interacts with other drugs that inhibit phosphodiesterases, such as sildenafil, leading to increased potency when taken together.</p>Formula:C22H30N6O3S2Purity:Min. 95%Color and Shape:PowderMolecular weight:490.64 g/molThiosildenafil
CAS:<p>Thiosildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil.</p>Formula:C22H30N6O3S2Color and Shape:SolidMolecular weight:490.64
