CAS 479347-85-8

CNQX disodium salt

Description:

CNQX disodium salt, with the CAS number 479347-85-8, is a potent and selective antagonist of the AMPA and kainate subtypes of glutamate receptors, which are critical for fast excitatory neurotransmission in the central nervous system. This compound is often utilized in neuropharmacological research to study synaptic transmission and plasticity, as well as to investigate the role of glutamate in various neurological disorders. CNQX disodium salt is typically characterized by its high solubility in water, making it suitable for in vitro experiments. Its chemical structure includes a quinoxaline backbone, which is essential for its receptor-binding properties. The disodium salt form enhances its stability and solubility, facilitating its use in biological assays. As a research tool, CNQX is valuable for elucidating the mechanisms of synaptic function and the effects of glutamate receptor modulation, contributing to our understanding of neurobiology and potential therapeutic targets for neurological diseases. Safety data sheets should be consulted for handling and storage guidelines, as with any chemical substance.

Formula: C₉H₂N₄O₄Na₂

Synonyms:

• 6-Cyano-7-nitroquinoxaline-2
• 3-dione disodium

CNQX disodium salt

CAS: 479347-85-8

Formula: C₉H₂N₄Na₂O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 276.1161

Ref: IN-DA00DLW3

CNQX disodium

CAS: 479347-85-8

CNQX disodium

Purity: ≥95%

Molecular weight: 276.12g/mol

Ref: 54-BUP13534

CNQX disodium

CAS: 479347-85-8

CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.

Formula: C₉H₂N₄Na₂O₄

Purity: 97.77%

Color and Shape: Solid

Molecular weight: 276.12

Ref: TM-T8458

CNQX Disodium Salt

Controlled Product

CAS: 479347-85-8

Formula: C₉H₂N₄Na₂O₄

Color and Shape: Neat

Molecular weight: 276.116

Ref: TR-C600003

CNQX disodium salt

CAS: 479347-85-8

CNQX disodium salt is a drug that inhibits the release of glutamate, an excitatory neurotransmitter. It has been shown to reduce locomotor activity in animals and to inhibit axonal growth in vitro. In vivo, CNQX disodium salt has been shown to inhibit both protein synthesis and neurotransmission in the cerebellum. The chronic exposure of CNQX disodium salt has been shown to induce symptoms similar to those seen in Alzheimer's disease patients, although this effect is reversible after withdrawal of the drug. CNQX disodium salt can also be used as an experimental model for studying how chronic exposure affects brain function. A study using rats demonstrated that CNQX disodium salt can decrease gamma-aminobutyric acid (GABA) levels by inhibiting calcium binding.

Formula: C₉H₂N₄Na₂O₄

Purity: Min. 95%

Molecular weight: 276.12 g/mol

Ref: 3D-EUA34785