CAS 479543-46-9

6-[carbamoyl(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)pyridine-3-carboxamide

Description:

The chemical substance known as 6-[carbamoyl(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)pyridine-3-carboxamide, with the CAS number 479543-46-9, is a complex organic compound characterized by its specific functional groups and structural features. It contains a pyridine ring, which is a six-membered aromatic heterocycle with nitrogen, and is substituted with various fluorinated phenyl groups. The presence of the carbamoyl and amine functional groups suggests potential for hydrogen bonding and interactions with biological targets, making it of interest in medicinal chemistry. The difluorophenyl substituents enhance its lipophilicity and may influence its pharmacokinetic properties. This compound may exhibit specific biological activities, potentially as an inhibitor or modulator in various biochemical pathways. Its synthesis and characterization would typically involve standard organic chemistry techniques, and its stability, solubility, and reactivity would be influenced by the presence of the fluorine atoms and the overall molecular structure. Further studies would be necessary to fully elucidate its properties and potential applications in drug development or other fields.

Formula: C₁₉H₁₂F₄N₄O₂

InChI: InChI=1/C19H12F4N4O2/c20-9-4-5-10(14(23)8-9)16-11(18(24)28)6-7-15(26-16)27(19(25)29)17-12(21)2-1-3-13(17)22/h1-8H,(H2,24,28)(H2,25,29)

SMILES: c1cc(c(c(c1)F)N(c1ccc(c(c2ccc(cc2F)F)n1)C(=N)O)C(=N)O)F

Synonyms:

• 3-Pyridinecarboxamide, 6-[(aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-
• 6-[Carbamoyl(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)nicotinamide
• 1-(5-CarbaMoyl-6-(2,4-difluorophenyl)pyridin-2-yl)-1-(2,6-difluorophenyl)urea
• Vx-702

6-​[(Aminocarbonyl)​(2,​6-​difluorophenyl)​amino]​-​2-​(2,​4-​difluorophenyl)​-3-​pyridinecarboxamide

CAS: 479543-46-9

6-​[(Aminocarbonyl)​(2,​6-​difluorophenyl)​amino]​-​2-​(2,​4-​difluorophenyl)​-3-​pyridinecarboxamide is a molecule that inhibits the activity of protein kinases and has been shown to be effective in the treatment of rheumatoid arthritis. 6-(Aminocarbonyl)-2-[(2,6-difluorophenyl)amino]-3-[(2,4-difluorophenyl)amino]pyridine carboxamide was developed by VX Pharma and is currently being investigated in clinical trials.

Formula: C₁₉H₁₂F₄N₄O₂

Purity: Min. 95%

Molecular weight: 404.3 g/mol

Ref: 3D-EUA54346