CAS 480-30-8

Dichloralphenazone

Description:

Dichloralphenazone, also known as chloral hydrate phenazone or by its chemical name, is a pharmaceutical compound primarily used for its analgesic and antipyretic properties. It is characterized by its molecular structure, which includes a phenazone moiety and two chlorine atoms attached to a carbon chain. This compound is typically presented as a white to off-white crystalline powder, which is soluble in organic solvents but has limited solubility in water. Dichloralphenazone acts by inhibiting the synthesis of prostaglandins, thereby reducing pain and fever. It is often utilized in combination with other medications to enhance therapeutic effects. The compound has a relatively low toxicity profile when used appropriately, but caution is advised due to potential side effects, including gastrointestinal disturbances and allergic reactions. As with many pharmaceuticals, it is essential to adhere to recommended dosages and consult healthcare professionals for guidance on its use. Overall, dichloralphenazone is a notable compound in the realm of analgesics, contributing to pain management in clinical settings.

Formula: C₁₁H₁₂N₂O·2C₂H₃Cl₃O₂

InChI: InChI=1S/C11H12N2O.C2H3Cl3O2/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10;3-2(4,5)1(6)7/h3-8H,1-2H3;1,6-7H

InChI key: InChIKey=MIMVDBNKZRBPLZ-UHFFFAOYSA-N

SMILES: C(C(O)O)(Cl)(Cl)Cl.CN1N(C(=O)C=C1C)C2=CC=CC=C2

Synonyms:

• 1,1-Ethanediol, 2,2,2-trichloro-, compd. with 1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one (2:1)
• 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one, compd. with 2,2,2-trichloro-1,1-ethanediol (1:2)
• 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one - 2,2,2-trichloroethane-1,1-diol (1:2)
• 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-2-phenyl-, compd. with 2,2,2-trichloro-1,1-ethanediol (1:2)
• Antipyrine, compd. with chloral hydrate (1:2)
• Antipyrine, compound with chloral hydrate (1:2)
• Bihypnal
• Bonadorm
• Chloral hydrate, compd. with antipyrine (2:1)
• DEA No. 2467
• Dichloralantipyrin
• Dichloralantipyrine
• Dichloralphenazone
• Dichloralphenazone [BAN]
• Dormuphar
• Dormwell
• Ibiodorm
• Kloralfenazon
• Sedor
• Sominat
• Unii-Yyx637R279
• Welldorm

Dichloralphenazone

Controlled Product

CAS: 480-30-8

Applications Dichloralphenazone is a combination of Antipyrine (A697500) and Chloral Hydrate (T774055), and is used to of induce sleep in insomniacs.
References Hindmarch, I. et al.: Arzneimitteforschung. 30, 1025 (1980); Hindmarch, I., et al.: Brit. J. Clin Pharmacol., 4, 229 (1977);

Formula: C₁₁H₁₂N₂O·2C₂H₃Cl₃O₂

Color and Shape: Neat

Molecular weight: 519.03

Ref: TR-D431700

Dichloralphenazone CIV (DISCONTINUED)

Controlled Product

CAS: 480-30-8

Aromatic or modified aromatic compounds containg an unfused pyrazolering (whether or not hydrogenated) in the structure

Formula: C₁₁H₁₂N₂O·2C₂H₃Cl₃O₂

Color and Shape: Powder

Molecular weight: 515.93469

Ref: 45-1187207