CAS 480-37-5

(-)-Pinostrobin

Description:

(-)-Pinostrobin is a naturally occurring flavonoid compound, primarily found in various plants, particularly in the ginger family and certain species of the genus Alpinia. It is characterized by its yellow crystalline appearance and has a molecular formula that reflects its complex structure, which includes multiple hydroxyl groups contributing to its reactivity and biological activity. This compound exhibits a range of pharmacological properties, including antioxidant, anti-inflammatory, and antimicrobial activities, making it of interest in both medicinal chemistry and natural product research. (-)-Pinostrobin is also noted for its potential in modulating various biological pathways, which may have implications for health and disease management. Its stereochemistry, indicated by the prefix "(-)", denotes its specific optical activity, which is crucial for its interaction with biological systems. Overall, (-)-Pinostrobin represents a significant compound in the study of natural products and their applications in health sciences.

Formula: C₁₆H₁₄O₄

InChI: InChI=1/C16H14O4/c1-19-11-7-12(17)16-13(18)9-14(20-15(16)8-11)10-5-3-2-4-6-10/h2-8,14,17H,9H2,1H3

InChI key: InChIKey=ORJDDOBAOGKRJV-AWEZNQCLSA-N

SMILES: O=C1C=2C(O[C@@H](C1)C3=CC=CC=C3)=CC(OC)=CC2O

Synonyms:

• (-)-2S-Pinocembrin
• (-)-Pinostrobin
• (2S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one
• (2S)-5-Hydroxy-7-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-on
• (2S)-5-Hydroxy-7-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
• (2S)-5-Hydroxy-7-methoxy-2-phenyl-2,3-dihydrochromen-4-one
• (2S)-Pinostrobin
• (S)-5-Hydroxy-7-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
• 480-37-5
• 4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (2S)-
• 4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (S)-
• 5-Hydroxy-7-methoxyflavanone
• 5-hydroxy-7-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
• 7-Methylpinocembrin
• Dihydrotectochrysin
• Flavanone, 5-hydroxy-7-methoxy-
• Pinocembrin-7-methyl ether
• Pinostrombin
• Pinostrobin,(S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one
• Pinostobin
• 5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one
• (S)-2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-4-benzopyrone
• 2-Phenyl-5-hydroxy-7-methoxy-2,3-dihydro-4H-1-benzopyran-4-one
• Pistrobin
• (S)-2,3-DIHYDRO-5-HYDROXY-7-METHOXY-2-PHENYL-4H-1-BENZOPYRAN-4-ONE
• 2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one

5-Hydroxy-7-methoxy-2-phenylchroman-4-one

CAS: 480-37-5

Formula: C₁₆H₁₄O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 270.2800

Ref: IN-DA006Y4O

Pinostrobin

CAS: 480-37-5

Formula: C₁₆H₁₄O₄

Purity: ≥ 98.0%

Color and Shape: White to yellow solid

Molecular weight: 270.28

Ref: 7W-GY9348

Pinostrobin

CAS: 480-37-5

Pinostrobin

Purity: ≥98%

Molecular weight: 270.28g/mol

Ref: 54-BUP17559

Pinostrobin

CAS: 480-37-5

Formula: C₁₆H₁₄O₄

Purity: 95%~99%

Molecular weight: 270.28

Ref: BP-SBP00113

Pinostrobin

CAS: 480-37-5

Pinostrobin protects PC12 cells from Aβ25-35 neurotoxicity by reducing oxidative stress, calcium excess, and blocking cell death pathways.

Formula: C₁₆H₁₄O₄

Purity: 99.35% - 99.55%

Color and Shape: Solid

Molecular weight: 270.28

Ref: TM-TN2082

Pinostrobin

CAS: 480-37-5

Formula: C₁₆H₁₄O₄

Molecular weight: 270.28

Ref: 4Z-P-272001

(-)-Pinostrobin

CAS: 480-37-5

(-)-Pinostrobin is a natural flavonoid compound, which is predominantly found in various plant species, including members of the genus *Cajanus* and *Zingiber*. As a chiral molecule, it exhibits bioactive properties leading to multiple pharmacological effects. The mode of action of (-)-Pinostrobin involves modulation of various biochemical pathways, including antioxidant, anti-inflammatory, and antimicrobial activities. It interacts with cellular enzymes and receptors, exerting its effects through inhibition of pro-inflammatory cytokines and enhancing cellular antioxidant defenses.

Formula: C₁₆H₁₄O₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 270.28 g/mol

Ref: 3D-XP180702

Pinostrombin

Controlled Product

CAS: 480-37-5

Applications Pinostrombin is a useful research chemical that can be used for chemical fingerprinting, isolating, and characterizing of polyphenol compounds. It can also be used as a potential compound for TMPRSS2 inhibition for Covid-19 therapy.
References Barrientos, R.E., et al.: Molecules, 25, 3105, (2020); Roomi, M.S., et al.: ChemRxiv, (2020);

Formula: C₁₆H₁₄O₄

Color and Shape: Neat

Molecular weight: 270.28

Ref: TR-H947653