CAS 480-75-1

Jaconine

Description:

Jaconine, with the CAS number 480-75-1, is a chemical compound classified as an alkaloid, specifically derived from the plant species *Jaconia*. It is known for its complex structure, which includes multiple rings and functional groups that contribute to its biological activity. Jaconine exhibits a range of pharmacological properties, including potential neuroprotective effects and interactions with various neurotransmitter systems. The compound is often studied for its effects on the central nervous system and its potential therapeutic applications. In terms of physical properties, jaconine is typically characterized by its solubility in organic solvents, while its stability can be influenced by environmental factors such as pH and temperature. As with many alkaloids, caution is advised when handling jaconine due to its bioactive nature, which may pose toxicity risks at certain concentrations. Research continues to explore its mechanisms of action and potential uses in medicine, particularly in the context of neurodegenerative diseases.

Formula: C₁₈H₂₅NO₈

InChI: InChI=1/C18H26ClNO6/c1-10-8-18(24,11(2)19)16(22)26-13-5-7-20-6-4-12(14(13)20)9-25-15(21)17(10,3)23/h4,10-11,13-14,23-24H,5-9H2,1-3H3

InChI key: InChIKey=CKPJPJSVQMEGBC-UHFFFAOYSA-N

SMILES: O=C1OC2C3N(CC2)CC=C3COC(=O)C(C)(O)C(C)CC1(C(C)Cl)O

Synonyms:

• [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-[(1R)-1-chloroethyl]-3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
• [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-(1-chloroethyl)-3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-5,6-dimethyl-, [3R-[3R*(R*),5R*,6S*,14aR*,14bR*]]-
• Senecionan-11,16-dione, 20-chloro-15,20-dihydro-12,15-dihydroxy-, (15α,20R)-
• Jaconine
• (3R,5R,6S,14aR,14bR)-3-[(1R)-1-Chloroethyl]-3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-5,6-dimethyl[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione
• (20R)-20-chloro-12,15-dihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione

Jaconine

CAS: 480-75-1

Jaconine, jacoline, jacobine, and jacozine: hepatotoxic, possibly carcinogenic, mutagenic, and teratogenic alkaloids, posing health risks.

Formula: C₁₈H₂₆ClNO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 387.86

Ref: TM-TN4346

Jaconine

CAS: 480-75-1

Natural alkaloid

Formula: C₁₈H₂₆NO₆Cl

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 387.86

Ref: 5G-83970

Jaconine

CAS: 480-75-1

Jaconine is a chemical compound that is an n-oxide of aconite roots. It has been shown to have inhibitory effects on cancer cells and infectious diseases. Jaconine inhibits the growth of various bacteria, including Staphylococcus aureus, Pseudomonas aeruginosa, and Salmonella enterica serovar Typhimurium. Jaconine also had an inhibitory effect on the development of skin cancer in tissue culture. The mechanism of action may be due to its ability to produce reactive oxygen species such as hydrogen chloride and specific antibodies against amines. This compound has been shown to have a protective effect on plants against diseases caused by fungi and other pathogens.

Formula: C₁₈H₂₆ClNO₆

Purity: Min. 95%

Molecular weight: 387.85 g/mol

Ref: 3D-FJ139146