CAS 4803-74-1

5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one

Description:

5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one is an organic compound characterized by its complex structure, which includes an indanone core substituted with methoxy groups and a pyridine moiety. This compound typically exhibits a yellow to orange color and is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), but may have limited solubility in water. The presence of methoxy groups enhances its lipophilicity, potentially influencing its biological activity and interaction with various receptors. The pyridine ring contributes to the compound's aromaticity and may play a role in its reactivity and binding properties. As a synthetic intermediate, it may be of interest in medicinal chemistry for the development of pharmaceuticals, particularly due to its potential biological activities, which could include anti-inflammatory or anticancer properties. However, specific biological data and toxicity profiles would need to be evaluated through experimental studies to fully understand its applications and safety.

Formula: C₁₇H₁₅NO₃

InChI: InChI=1/C17H15NO3/c1-20-15-9-12-8-13(7-11-3-5-18-6-4-11)17(19)14(12)10-16(15)21-2/h3-7,9-10H,8H2,1-2H3/b13-7+

Synonyms:

• 5,6-Dimethoxy-2-(pyridin-4-yl)methylene-indan-1-one
• 2,3-Dihydro-5,6-dimethoxy-2-(4-pyridinylmethylene)-1H-inden-1-one
• 5,6-dimethoxy-2-(4-pyridylmethylene)-1-Indanone
• (2E)-5,6-dimethoxy-2-(pyridin-4-ylmethylidene)-2,3-dihydro-1H-inden-1-one

1H-​Inden-​1-​one, 2,​3-​dihydro-​5,​6-​dimethoxy-​2-​(4-​pyridinylmethylene)​-

CAS: 4803-74-1

Formula: C₁₇H₁₅NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 281.3059

Ref: IN-DA00IMLW

5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one

CAS: 4803-74-1

5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one

Purity: 98%

Molecular weight: 281.31g/mol

Ref: 54-OR1011772

5,6-Dimethoxy-2-[(4-pyridyl)methylene]indan-1-one

Controlled Product

CAS: 4803-74-1

Formula: C₁₇H₁₅NO₃

Color and Shape: Neat

Molecular weight: 281.31

Ref: 86-MM0677.13

Donepezil Impurity 36

CAS: 4803-74-1

Formula: C₁₇H₁₅NO₃

Molecular weight: 281.31

Ref: 4Z-D-1364

Donepezil Pyridine Dehydro Impurity

CAS: 4803-74-1

Formula: C₁₇H₁₅NO₃

Molecular weight: 281.31

Ref: ST-EA-CP-D2029

5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone (Donepezil Impurity)

Controlled Product

CAS: 4803-74-1

Impurity Donepezil Pyridine Dehydro Impurity
Applications An impurity of Donepezil.
References Dooley, M., et al.: Drugs Aging, 16, 199 (2000), Gotti, R., et al.: J. Pharm. Biomed. Anal., 24, 863 (2001), Gotti, R., et al.: Anal. Bioanal. Chem., 377, 875 (2003),

Formula: C₁₇H₁₅NO₃

Color and Shape: Neat

Molecular weight: 281.31

Ref: TR-D460720

5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone

CAS: 4803-74-1

5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is a hydroxide that is obtained by the reflux of 4-hydroxybenzaldehyde with an alkali metal hydroxide. It can be used in the synthesis of benzylated donepezil hydrochloride. 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone condenses with pyridinecarboxaldehyde to produce 1-(4'-pyridylmethylene)indane. This reaction produces a mixture of products, including benzoic acid and the indane derivative.

Formula: C₁₇H₁₅NO₃

Purity: Min. 95%

Molecular weight: 281.31 g/mol

Ref: 3D-ID22170