CAS 480438-42-4

Chloro[[3-(trifluoromethyl)phenyl]methyl]zinc

Description:

Chloro[[3-(trifluoromethyl)phenyl]methyl]zinc, identified by its CAS number 480438-42-4, is an organozinc compound characterized by the presence of a zinc atom coordinated to a chloro group and a 3-(trifluoromethyl)phenylmethyl moiety. This compound typically exhibits properties associated with organometallics, such as reactivity towards electrophiles and potential use in cross-coupling reactions, making it valuable in organic synthesis. The trifluoromethyl group enhances the lipophilicity and electron-withdrawing characteristics of the phenyl ring, which can influence the compound's reactivity and stability. Chloro[[3-(trifluoromethyl)phenyl]methyl]zinc is often handled under inert atmospheres due to its sensitivity to moisture and air, which can lead to hydrolysis or oxidation. Its applications may include serving as a reagent in the formation of carbon-carbon bonds, particularly in the synthesis of complex organic molecules. As with many organozinc compounds, safety precautions should be observed due to potential toxicity and reactivity.

Formula: C₈H₆ClF₃Zn

InChI: InChI=1/C8H6F3.ClH.Zn/c1-6-3-2-4-7(5-6)8(9,10)11;;/h2-5H,1H2;1H;/q-1;;+2/p-1/rC8H6F3.ClZn/c1-6-3-2-4-7(5-6)8(9,10)11;1-2/h2-5H,1H2;/q-1;+1

InChI key: InChIKey=WNPDTQVRJMVKON-UHFFFAOYSA-M

SMILES: C(F)(F)(F)C1=CC(C[Zn]Cl)=CC=C1

Synonyms:

• [3-(Trifluoromethyl)benzyl]zinc chloride
• Chloro[[3-(trifluoromethyl)phenyl]methyl]zinc
• Zinc, chloro[[3-(trifluoromethyl)phenyl]methyl]-
• 3-Trifluoromethylbenzylzinc chloride 0.5 M in Tetrahydrofuran
• chlorozinc(1+),1-methanidyl-3-(trifluoromethyl)benzene
• 3-(Trifluoromethyl)benzylzinc chloride solution 0.5 in THF
• 3-(TRIFLUOROMETHYL)BENZYLZINC CHLORIDE,0.5M SOLUTION IN TETRAHYDROFURAN
• 3-(trifluoromethyl)benzylzinc chloride solution
• 3-(TRIFLUOROMETHYL)BENZYLZINC CHLORIDE
• 3-(Trifluoromethyl)benzylzinc chloride solution 0.5M in THF