CAS 480438-46-8

Chloro[(2-methoxyphenyl)methyl]magnesium

Description:

Chloro[(2-methoxyphenyl)methyl]magnesium, with the CAS number 480438-46-8, is an organomagnesium compound that belongs to the class of Grignard reagents. This compound typically features a magnesium atom bonded to a chloro group and a 2-methoxyphenylmethyl group, which contributes to its reactivity and utility in organic synthesis. Grignard reagents are known for their ability to act as nucleophiles, enabling them to react with a variety of electrophiles, including carbonyl compounds, to form alcohols. The presence of the methoxy group enhances the electron density on the aromatic ring, potentially influencing the reactivity and selectivity of the compound in synthetic applications. Chloro[(2-methoxyphenyl)methyl]magnesium is typically handled under anhydrous conditions due to its sensitivity to moisture, which can lead to hydrolysis and the formation of unwanted byproducts. Overall, this compound serves as a valuable intermediate in the synthesis of more complex organic molecules.

Formula: C₈H₉ClMgO

InChI: InChI=1S/C8H9O.ClH.Mg/c1-7-5-3-4-6-8(7)9-2;;/h3-6H,1H2,2H3;1H;/q;;+1/p-1

InChI key: InChIKey=JJNLSBBAAQTDSM-UHFFFAOYSA-M

SMILES: C([Mg]Cl)C1=C(OC)C=CC=C1

Synonyms:

• Chloro[(2-methoxyphenyl)methyl]magnesium
• Magnesium, chloro[(2-methoxyphenyl)methyl]-

2-Methoxybenzylmagnesium chloride, 0.25M in 2-MeTHF

CAS: 480438-46-8

2-Methoxybenzylmagnesium chloride is a Grignard reagent used in organic synthesis. It is involved in the synthesis of (-)-Chamobtusin A. It is also used in the preparation of molybdenum and tungsten Alkylidene complexes having a tert-butylimido ligand. This Thermo Scientific Chemicals brand product

Formula: C₈H₉ClMgO

Molecular weight: 180.92

Ref: 02-H54177