CAS 481-21-0

5α-Cholestane

Description:

5α-Cholestane, with the CAS number 481-21-0, is a saturated sterol and a derivative of cholesterol. It is characterized by a rigid, multi-ring structure typical of steroid compounds, featuring a total of 27 carbon atoms and a molecular formula of C27H46. This compound is notable for its lack of double bonds, which distinguishes it from its unsaturated counterparts. 5α-Cholestane is typically found in various biological systems and can be derived from the hydrogenation of cholesterol. It is insoluble in water but soluble in organic solvents, reflecting its hydrophobic nature. The compound is often used in biochemical research and as a reference standard in analytical chemistry, particularly in studies involving sterols and lipid metabolism. Its stability and structural integrity make it a valuable substance for understanding the behavior of sterols in biological systems. Additionally, 5α-Cholestane can serve as a biomarker for certain geological and biological processes, contributing to the study of ancient organisms and environmental conditions.

Formula: C₂₇H₄₈

InChI: InChI=1S/C27H48/c1-19(2)9-8-10-20(3)23-14-15-24-22-13-12-21-11-6-7-17-26(21,4)25(22)16-18-27(23,24)5/h19-25H,6-18H2,1-5H3/t20-,21-,22+,23-,24+,25+,26+,27-/m1/s1

InChI key: InChIKey=XIIAYQZJNBULGD-XWLABEFZSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@@](CC3)(CCCC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]

Synonyms:

• (20R)-5α(H),14α(H),17α(H)-Cholestane
• (5Alpha,8Xi,9Xi,14Xi,17Xi,20Xi)-Cholestane
• (5R,8R,9S,10S,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene
• 28,29,30-Trinorlanostane
• 5-Alpha-Cholestane
• 5A-cholestane
• Cholestan
• Cholestane
• Cholestane, (5α)-
• NSC 224419
• α-Cholestane

(5-α)-Cholestane

CAS: 481-21-0

(5-alpha)-Cholestane analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₂₇H₄₈

Purity: (GC) ≥95%

Color and Shape: Powder

Molecular weight: 372.68

Ref: 11-3553

5α-Cholestane

CAS: 481-21-0

Formula: C₂₇H₄₈

Purity: 97%

Color and Shape: Solid

Molecular weight: 372.6700

Ref: IN-DA003MC0

5α-Cholestane

CAS: 481-21-0

5α-Cholestane

Purity: ≥98%

Molecular weight: 372.67g/mol

Ref: 54-BUP16429

5α-Cholestane-3,3-d2

CAS: 122241-86-5, 481-21-0

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 374.69

Ref: 3U-D5323

5α-Cholestane-2,2,3,3,4,4-d6

CAS: 358731-18-7, 481-21-0

Purity: 95 atom % D

Color and Shape: White Solid

Molecular weight: 378.71

Ref: 3U-D5535

5-α-Cholestane

CAS: 481-21-0

Formula: C27H48

Purity: >96%

Color and Shape: White Powder

Molecular weight: 372.67

Ref: 48-60-1019

5α-Cholestane

Controlled Product

CAS: 481-21-0

Formula: C₂₇H₄₈

Color and Shape: Neat

Molecular weight: 372.67

Ref: 04-C11665380

5α-Cholestane

CAS: 481-21-0

5α-Cholestane belongs to the cholestane steroid class of compounds.

Formula: C₂₇H₄₈

Purity: 99.02% - 99.44%

Color and Shape: Solid

Molecular weight: 372.67

Ref: TM-T8043

5-alfa-Cholestane

CAS: 481-21-0

Formula: C₂₇H₄₈

Molecular weight: 372.68

Ref: 4Z-C-5367

Alpha-Cholestane

Controlled Product

CAS: 481-21-0

Applications α-Cholestane is the trans-decalin homolog of Coprostane.
References Ruzicka, et al.: Helv. Chim. Acta, 16, 327 (1933), Yamaga, N., et al.: J. Biochem., 119, 725 (1996), Burkard, I., et al.: J. Lipid Res., 45, 776 (2004), Teng, S., et al.: Br. J. Pharmacol., 151, 367 (2007),

Formula: C₂₇H₄₈

Color and Shape: White To Off-White

Molecular weight: 372.67

Ref: TR-C431700

α-Cholestane

Controlled Product

CAS: 481-21-0

a-Cholestane is a fatty acid that is an intermediate in the biosynthesis of cholesterol. It can be found in urine samples as a result of its conversion by the enzyme lecithin:cholesterol acyltransferase (LCAT). LCAT catalyzes the transfer of cholesteryl ester from plasma lipoproteins to the polar head group of phosphatidylcholine, which then becomes lecithin. The LCAT reaction is reversible and is catalyzed by sodium taurocholate. Magnetic resonance spectroscopy can be used to analyze how LCAT affects the surface methodology of a-cholestane.

Formula: C₂₇H₄₈

Purity: (%) Min. 97%

Color and Shape: Powder

Molecular weight: 372.67 g/mol

Ref: 3D-FC20419

5α-Cholestane

CAS: 481-21-0

Formula: C₂₇H₄₈

Molecular weight: 372.68

Ref: ST-EA-CP-C71008