CAS 481047-48-7

(+)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile

Description:

The chemical substance known as (+)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile, with the CAS number 481047-48-7, is a synthetic organic compound that belongs to the class of benzonitriles. It features a complex structure characterized by a benzonitrile core, which is substituted with a hydroxymethyl group and a dimethylamino group, as well as a fluorophenyl moiety. This compound exhibits chirality, indicated by the presence of the "(+)" prefix, suggesting it has a specific optical activity. The dimethylamino group contributes to its potential as a pharmacophore, possibly influencing its biological activity and interactions with various receptors. The presence of the fluorine atom may enhance lipophilicity and metabolic stability. Overall, this compound's unique structural features may render it of interest in medicinal chemistry, particularly in the development of therapeutic agents. However, specific biological activities, solubility, and stability would require further investigation through empirical studies.

Formula: C₂₀H₂₃FN₂O₂

InChI: InChI=1S/C20H23FN2O2/c1-23(2)11-3-10-20(25,17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24/h4-9,12,24-25H,3,10-11,14H2,1-2H3/t20-/m1/s1

InChI key: InChIKey=GNULRNVWXYXBQY-HXUWFJFHSA-N

SMILES: [C@](CCCN(C)C)(O)(C1=C(CO)C=C(C#N)C=C1)C2=CC=C(F)C=C2

Synonyms:

• Benzonitrile, 4-[(1R)-4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-
• (R)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile
• (+)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile
• 4-[(1R)-4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile
• (R)-Citadiol

(R)-Citadiol

CAS: 481047-48-7

Formula: C₂₀H₂₃FN₂O₂

Molecular weight: 342.41

Ref: 4Z-C-0960

(R)-Citadiol

Controlled Product

CAS: 481047-48-7

Applications (R)-Citadiol is an intermediate in the synthesis of (R)-Citalopram Oxalate (C505015), an inhibitor of serotonin (5-HT) uptake. Antidepressant.
References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977); Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000); Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001); Fish, E.W., et al.: J. Pharmacol. Exp. Ther, 308, 474 (2004)

Formula: C₂₀H₂₃FN₂O₂

Color and Shape: Neat

Molecular weight: 342.407

Ref: TR-C504805

(R)-Citadiol

CAS: 481047-48-7

(R)-Citadiol is a potent inhibitor of cancer cell growth and tumor formation. It works by targeting specific proteins involved in the cell cycle and inducing apoptosis, or programmed cell death. This medicinal compound has been shown to be effective against various types of cancer, including breast, prostate, and lung cancers. (R)-Citadiol is an analog of a natural product found in Chinese medicinal plants and has been isolated from human urine. It acts as a kinase inhibitor, blocking the activity of enzymes that promote cancer cell growth and proliferation. With its strong anticancer properties, (R)-Citadiol holds great promise as a potential treatment for cancer.

Formula: C₂₀H₂₃FN₂O₂

Purity: Min. 95%

Molecular weight: 342.4 g/mol

Ref: 3D-GUA04748

Citadiol

CAS: 481047-48-7

Formula: C₂₀H₂₃FN₂O₂

Molecular weight: 342.41

Ref: ST-EA-CP-C23084