CymitQuimica logo

CAS 482-67-7

:

3′-Phosphoadenosine 5′-phosphosulfate

Description:
3′-Phosphoadenosine 5′-phosphosulfate (commonly abbreviated as PAPS) is a key biochemical compound involved in sulfate activation and the biosynthesis of sulfated biomolecules. It is a nucleotide sulfate, consisting of an adenosine moiety linked to two phosphate groups and a sulfate group. PAPS serves as a universal sulfate donor in various biological processes, particularly in the sulfation of carbohydrates, proteins, and lipids, which is crucial for cellular signaling and the regulation of biological activities. The compound is typically found in the cytosol of cells and is synthesized from ATP and inorganic sulfate through the action of the enzyme adenosine 5′-phosphosulfate kinase. PAPS is highly soluble in water, making it readily available for enzymatic reactions. Its stability is influenced by pH and temperature, and it can be hydrolyzed to adenosine 5′-phosphate (AMP) and sulfate under certain conditions. Overall, PAPS plays a vital role in cellular metabolism and the maintenance of sulfation processes in living organisms.
Formula:C10H15N5O13P2S
InChI:InChI=1S/C10H15N5O13P2S/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7(27-29(17,18)19)4(26-10)1-25-30(20,21)28-31(22,23)24/h2-4,6-7,10,16H,1H2,(H,20,21)(H2,11,12,13)(H2,17,18,19)(H,22,23,24)/t4-,6-,7-,10-/m1/s1
InChI key:InChIKey=GACDQMDRPRGCTN-KQYNXXCUSA-N
SMILES:O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OS(=O)(=O)O)(=O)O)[C@H]1OP(=O)(O)O
Synonyms:
  • Adenosine 3′-phosphate 5′-phosphosulfate
  • Adenosine, 3′,5′-bis(dihydrogen phosphate), 5′-monoanhydride with sulfuric acid
  • Adenosine 3′,5′-diphosphate, 5′-anhydride with sulfuric acid
  • 3′-Adenylic acid, 5′-(dihydrogen phosphate), 5′-anhydride with sulfuric acid
  • PAPS
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.