CAS 483-09-0

methyl (3beta,16beta,17alpha,20alpha)-17-hydroxyyohimban-16-carboxylate

Description:

Methyl (3beta,16beta,17alpha,20alpha)-17-hydroxyyohimban-16-carboxylate, with CAS number 483-09-0, is a chemical compound derived from yohimbine, which is an indole alkaloid. This substance is characterized by its complex structure, featuring a yohimban skeleton that includes multiple stereocenters, contributing to its specific three-dimensional configuration. It typically appears as a white to off-white crystalline solid and is soluble in organic solvents, but its solubility in water is limited. The compound exhibits biological activity, particularly in the context of its potential effects on the central nervous system and its use in various pharmacological applications, including as an aphrodisiac and in the treatment of erectile dysfunction. Its mechanism of action is thought to involve the antagonism of alpha-2 adrenergic receptors, which can enhance norepinephrine release. As with many alkaloids, it may also have side effects and contraindications, necessitating careful consideration in therapeutic contexts. Overall, this compound is of interest in both medicinal chemistry and pharmacology due to its unique properties and potential applications.

Formula: C₂₁H₂₆N₂O₃

InChI: InChI=1/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17-,18+,19+/m1/s1

Synonyms:

• 3-epi-alpha-Yohimbine
• 3-epi-a-Yohimbine
• Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (3beta,16beta,17alpha,20alpha)-

(3β,20α)-17α-Hydroxyyohimban-16β-carboxylic acid methyl ester

CAS: 483-09-0

Formula: C₂₁H₂₆N₂O₃

Purity: 98.0%

Molecular weight: 354.4427

Ref: IN-DA00DGZ6

Isorauhimbine

CAS: 483-09-0

Isorauhimbine is an alkaloid derived from R. serpentina that has anticancer and antibacterial activity and is used to treat high blood pressure.

Formula: C₂₁H₂₆N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 354.44

Ref: TM-TN4323

Isorauhimbine

CAS: 483-09-0

Formula: C₂₁H₂₆N₂O₃

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 354.45

Ref: BP-SBP00510

Isorauhimbin

Controlled Product

CAS: 483-09-0

Applications Isorauhimbin, is a novel plant-derived molecule of Rauvolfia serpentina that can be used as an inhibitor of aldose reductase, a potent drug target for diabetes and its complications.
References Pathania, Sh. et al.: PLoS One, Vol. 8, P: 61327 (2013);

Formula: C₂₁H₂₆N₂O₃

Color and Shape: Neat

Molecular weight: 354.44

Ref: TR-I789270

Isorauhimbin

CAS: 483-09-0

Isorauhimbin is an indole alkaloid, which is derived from the plant family Apocynaceae. It is primarily sourced from the bark of Rauwolfia plants, where it exists as one of the stereoisomers of yohimbine. The mode of action of Isorauhimbin involves its interaction with adrenergic receptors, specifically acting as an antagonist at the alpha-2 adrenergic receptors. This interaction results in increased release of norepinephrine and enhanced sympathetic nervous system activity.

Formula: C₂₁H₂₆N₂O₃

Purity: Min. 95%

Molecular weight: 354.4 g/mol

Ref: 3D-AAA48309