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CAS 4847-29-4

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Phenoxymethylpenilloic Acid

Description:
Phenoxymethylpenicillinic acid, also known as phenoxymethylpenicillin or penicillin V, is a beta-lactam antibiotic that is derived from penicillin. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a variety of gram-positive bacteria. The compound features a phenoxymethyl group that enhances its stability in acidic environments, allowing for oral administration. It is generally less effective against penicillinase-producing bacteria compared to other penicillins. Phenoxymethylpenicillin is commonly used to treat infections such as streptococcal pharyngitis, skin infections, and certain respiratory tract infections. Its pharmacokinetics include good absorption from the gastrointestinal tract, with peak plasma concentrations occurring within a few hours after ingestion. The substance is typically administered in the form of its potassium salt to improve solubility. Side effects may include allergic reactions, gastrointestinal disturbances, and, in rare cases, superinfection due to disruption of normal flora. Overall, phenoxymethylpenicillin remains a valuable antibiotic in clinical practice, particularly for infections caused by susceptible organisms.
Formula:C15H20N2O4S
InChI:InChI=1/C15H20N2O4S/c1-15(2)13(14(19)20)17-12(22-15)8-16-11(18)9-21-10-6-4-3-5-7-10/h3-7,12-13,17H,8-9H2,1-2H3,(H,16,18)(H,19,20)
SMILES:CC1(C)C(C(=O)O)NC(CN=C(COc2ccccc2)O)S1
Synonyms:
  • 5,5-Dimethyl-2-{[(Phenoxyacetyl)Amino]Methyl}-1,3-Thiazolidine-4-Carboxylic Acid
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