CAS 4849-90-5

ARISTOLOCHIC ACID C

Description:

Aristolochic Acid C (AAC) is a naturally occurring compound derived from plants in the Aristolochiaceae family, particularly from the genus Aristolochia. It is known for its potent biological activity, including its role as a nephrotoxin and potential carcinogen. AAC is characterized by its complex structure, which includes a bicyclic system and a carboxylic acid functional group. The compound exhibits a range of pharmacological effects, but its use is limited due to its toxicity and association with kidney damage and urothelial cancers. In terms of solubility, AAC is generally soluble in organic solvents but has limited solubility in water. Its chemical properties make it a subject of interest in toxicology and pharmacology, particularly concerning its mechanisms of action and the implications of exposure. Due to its adverse health effects, the use of Aristolochia species containing AAC is restricted in many countries, highlighting the importance of safety and regulatory considerations in herbal medicine.

Formula: C₁₆H₉NO₇

InChI: InChI=1/C16H9NO7/c18-8-2-1-7-3-11(17(21)22)13-10(16(19)20)5-12-15(24-6-23-12)14(13)9(7)4-8/h1-5,18H,6H2,(H,19,20)

SMILES: c1cc(cc2c1cc(c1c(cc3c(c21)OCO3)C(=O)O)N(=O)=O)O

Synonyms:

• 10-Hydroxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid
• Phenanthro[3,4-D]-1,3-Dioxole-5-Carboxylic Acid, 10-Hydroxy-6-Nitro-

Phenanthro[3,4-d]-1,3-dioxole-5-carboxylicacid, 10-hydroxy-6-nitro-

CAS: 4849-90-5

Formula: C₁₆H₉NO₇

Purity: 95%

Color and Shape: Solid

Molecular weight: 327.2452

Ref: IN-DA006WTF

Aristolochic acid C

CAS: 4849-90-5

Formula: C₁₆H₉NO₇

Molecular weight: 327.25

Ref: 7W-GY9310

Aristolochic acid C

CAS: 4849-90-5

Aristolochic acid C

Purity: ≥98%

Molecular weight: 327.25g/mol

Ref: 54-BUP00386

Aristolochic acid C

CAS: 4849-90-5

Formula: C₁₆H₉NO₇

Purity: 95%~99%

Molecular weight: 327.248

Ref: BP-BPF0516

Aristolochic acid C

CAS: 4849-90-5

Aristolochic acid C is a derivative of Aristolochic acid which is a phospholipase A2 inhibitor.

Formula: C₁₆H₉NO₇

Purity: 99.8%

Color and Shape: White Powder

Molecular weight: 327.25

Ref: TM-TN1064

Aristolochic acid c

CAS: 4849-90-5

Carboxylic acid with additional oxygen functions

Formula: C₁₆H₉NO₇

Purity: ≥ 70.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 327.25

Ref: 5G-80355

Aristolochic acid C

CAS: 4849-90-5

Aristolochic acid C is a naturally occurring alkaloid derivative, which is extracted from plants in the Aristolochiaceae family. These compounds are known to be present in various species, including Aristolochia and Asarum. Aristolochic acid C is known for its mutagenic and carcinogenic properties, primarily due to its ability to form covalent DNA adducts. This interaction leads to a high frequency of DNA mutations, contributing to cellular dysfunction and malignant transformations.

Formula: C₁₆H₉NO₇

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 327.25 g/mol

Ref: 3D-FA17984