CAS: 485-49-4 - (+)-Bicuculline

Formula: C₂₀H₁₈NO₆

InChI: InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1

InChI key: InChIKey=IYGYMKDQCDOMRE-ZWKOTPCHSA-N

SMILES: O=C1OC(C2=CC=C3OCOC3=C12)C4C5=CC=6OCOC6C=C5CCN4C

Synonyms:

• (5S)-6-methyl-5-[(6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium
• (6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one
• (6R)-6-[(5S)-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one
• (R-(R*,S*))-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-furo(3,4-e)-1,3-benzodioxol-8(6H)-one
• 1,3-Dioxolo[4,5-g]isoquinoline, furo[3,4-e]-1,3-benzodioxol-8(6H)-one deriv.
• 6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[4,3-g][1,3]benzodioxol-8-one
• Bicuculina
• Bicucullin
• Bucuculline
• Furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [R-(R*,S*)]-
• Furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 6-[(5S)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (6R)-
• Nsc 32192
• d-Bicuculline

(+)-Bicuculline

CAS: 485-49-4

• Formula: C₂₀H₁₇NO₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 367.3521

Bicuculline

CAS: 485-49-4

• Formula: C₂₀H₁₇NO₆
• Purity: 95%~99%
• Molecular weight: 367.357

(+)-Bicuculline

CAS: 485-49-4

• Formula: C₂₀H₁₇NO₆
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Yellow to Orange powder to crystal
• Molecular weight: 367.36

(+)-Bicuculline

CAS: 485-49-4

• Formula: C₂₀H₁₇NO₆
• Molecular weight: 367.35

Bicuculline

CAS: 485-49-4

Bicuculline ((+)-Bicuculline) is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in …

• Formula: C₂₀H₁₇NO₆
• Purity: 99.99%
• Color and Shape: Light Yellow Powder
• Molecular weight: 367.35

(+)-bicuculline

CAS: 485-49-4

Natural alkaloid

• Formula: C₂₀H₁₇NO₆
• Purity: ≥ 98.0 % (HPLC)
• Color and Shape: Powder
• Molecular weight: 367.36

Bicuculline

CAS: 485-49-4

Applications Alkaloid naturally occurring in the d-form. Shows GABA antagonist activity. References Curtis, et al.: …

• Formula: C₂₀H₁₇NO₆
• Color and Shape: Off-White to Pale Yellow Solid
• Molecular weight: 367.35

(+)-Bicuculline

CAS: 485-49-4

(+)-Bicuculline is a plant alkaloid that has been shown to have anti-inflammatory effects, as well …

• Formula: C₂₀H₁₇NO₆
• Molecular weight: 367.36 g/mol

(+)-Bicuculline - Bio-X ™

CAS: 485-49-4

Bicuculline is a phthalide-isoquinoline compound and is a competitive GABA receptor antagonist. It blocks GABA’s …

• Formula: C₂₀H₁₇NO₆
• Purity: Min. 99 Area-%
• Color and Shape: Powder
• Molecular weight: 367.35 g/mol

(+)-Bicuculline

CAS: 485-49-4

Inhibitor of ionotropic receptor GABA(A)

• Formula: C₂₀H₁₇NO₆
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 367.35 g/mol