CAS 485-64-3

Dihydrocinchonidine

Description:

Dihydrocinchonidine is an alkaloid derived from the bark of the cinchona tree, known for its role in the treatment of malaria and its use as a chiral auxiliary in asymmetric synthesis. It is a white to off-white crystalline solid with a complex molecular structure that includes a bicyclic framework. The compound exhibits optical activity due to the presence of chiral centers, making it valuable in enantioselective reactions. Dihydrocinchonidine has a relatively low solubility in water but is soluble in organic solvents such as ethanol and chloroform. Its chemical properties include the ability to form salts with acids, which can enhance its solubility and stability. The substance is also known for its potential pharmacological effects, including analgesic and antipyretic properties. Safety data indicates that, like many alkaloids, it should be handled with care due to potential toxicity at higher concentrations. Overall, dihydrocinchonidine is significant in both medicinal chemistry and synthetic organic chemistry applications.

Formula: C₁₉H₂₄N₂O

InChI: InChI=1S/C19H24N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h3-7,9,13-14,18-19,22H,2,8,10-12H2,1H3/t13-,14-,18-,19+/m0/s1

InChI key: InChIKey=WFJNHVWTKZUUTR-KODHJQJWSA-N

SMILES: [C@H](O)([C@]1([N@@]2C[C@H](CC)[C@](C1)(CC2)[H])[H])C=3C4=C(N=CC3)C=CC=C4

Synonyms:

• (-)-Dihydrocinchonidine
• (8alpha,9R)-10,11-Dihydrocinchonan-9-ol
• 10,11-Dihydrocinchonan-9-Ol
• 10,11-Dihydrocinchonidine
• Cinchamidine
• Cinchonan-9-ol, 10,11-dihydro-, (8α,9R)-
• Hydrocinchonidine
• (8α,9R)-10,11-Dihydrocinchonan-9-ol

Hydrocinchonidine

CAS: 485-64-3

Formula: C₁₉H₂₄N₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 296.41

Ref: 3B-H1702

Dihydrocinchonidine ((R)-[(2S,4S,5R)-5-Ethylquinuclidin-2-yl](quinolin-4-yl)methanol)

CAS: 485-64-3

Alkaloids of cinchona (excluding quinine and its salts) and their derivatives; salts thereof

Formula: C₁₉H₂₄N₂O

Color and Shape: White Powder

Molecular weight: 296.41

Ref: 45-1A08700

(8α,9R)-10,11-DIHYDROCINCHONAN-9-OL

CAS: 485-64-3

Formula: C₁₉H₂₄N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 296.4067

Ref: IN-DA00DFF6

Cinchamidine

CAS: 485-64-3

Cinchamidine

Purity: 98%

Molecular weight: 296.41g/mol

Ref: 54-OR1027275

Dihydrocinchonidine

CAS: 485-64-3

Formula: C₁₉H₂₄N₂O

Molecular weight: 296.41

Ref: 4Z-C-483002

Cinchamidine

Controlled Product

CAS: 485-64-3

Formula: C₁₉H₂₄N₂O

Color and Shape: Neat

Molecular weight: 296.407

Ref: TR-C441945

Hydrocinchonidine

CAS: 485-64-3

Hydrocinchonidine is a phosphorus pentachloride that can be used as an anti-malarial drug. It is a bifunctional molecule and has been shown to have biological properties. In addition, hydrocinchonidine has been found to be effective in the synthesis of quinoline derivatives with a fluorine atom. Hydrocinchonidine is also used in skin tests for allergic reactions and as a preservative in topical medications.

Formula: C₁₉H₂₄N₂O

Purity: Min. 95%

Molecular weight: 296.41 g/mol

Ref: 3D-AAA48564