CAS 485395-71-9

Aminohexylgeldanamycin

CAS: 485395-71-9

Aminohexylgeldanamycin is an analog of the antibiotic geldanamycin that has been shown to have potent anticancer activity. It acts as an inhibitor of the heat shock protein 90 (Hsp90), which plays a crucial role in the folding and stabilization of many proteins, including kinases that are involved in cancer cell growth and survival. Aminohexylgeldanamycin induces apoptosis in cancer cells by disrupting Hsp90 function, leading to degradation of client proteins involved in tumor growth and survival. It has been shown to be effective against human cancer cell lines, as well as Chinese hamster ovary cells, and has demonstrated promising results in preclinical studies. Aminohexylgeldanamycin is not active against surfactin or any other bacterial species found in urine.

Formula: C₃₄H₅₂N₄O₈

Purity: Min. 95%

Molecular weight: 644.8 g/mol

Ref: 3D-KUA39571

Aminohexylgeldanamycin

CAS: 485395-71-9

AHGDM, a Geldanamycin derivative, inhibits HSP90 with strong antiangiogenic and antitumor effects.

Formula: C₃₄H₅₂N₄O₈

Color and Shape: Solid

Molecular weight: 644.8

Ref: TM-T37377