CAS 486-16-8: (±)-Carbinoxamine

Description: (±)-Carbinoxamine is an antihistamine with anticholinergic properties, primarily used to alleviate allergy symptoms. It is classified as a first-generation antihistamine, which means it can cross the blood-brain barrier, often leading to sedation as a side effect. The substance is a racemic mixture, containing both enantiomers, which can exhibit different pharmacological effects. Its chemical structure includes a piperidine ring, contributing to its activity as a histamine H1 receptor antagonist. (±)-Carbinoxamine is typically administered orally and is effective in treating allergic rhinitis, urticaria, and other allergic conditions. The compound is also known for its potential to cause side effects such as dry mouth, dizziness, and drowsiness, which are common among first-generation antihistamines. Due to its sedative effects, caution is advised when operating machinery or driving after consumption. Additionally, it is important to consider drug interactions, especially with other central nervous system depressants. Overall, (±)-Carbinoxamine serves as a useful therapeutic agent in managing allergic reactions, albeit with a profile that necessitates careful monitoring of its effects.

Formula: C₁₆H₁₉ClN₂O

InChI: InChI=1S/C16H19ClN2O/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13/h3-10,16H,11-12H2,1-2H3

InChI key: InChIKey=OJFSXZCBGQGRNV-UHFFFAOYSA-N

SMILES: ClC1=CC=C(C=C1)C(OCCN(C)C)C2=NC=CC=C2

Synonyms:

• 2-(4-Chloro-Alpha-(2-Pyridyl)Benzyloxy)Ethyldimethylamine
• 2-[(4-Chlorophenyl)-2-Pyridinylmethoxy]-N,N-Dimethylethanamine
• 2-[P-Chloro-A-(2-Dimethylaminoethoxy)Benzyl]Pyridine
• 2-[p-Chloro-α-[2-(dimethylamino)ethoxy]benzyl]pyridine
• Carbinoxamin
• Carbinoxamina
• Carbinoxamine (base and/or unspecified salts)
• Ethanamine, 2-[(4-chlorophenyl)-2-pyridinylmethoxy]-N,N-dimethyl-
• McN-R 73Z
• Paracarbinoxamine
• Paracarinoxamine
• Pyridine, 2-[p-chloro-α-[2-(dimethylamino)ethoxy]benzyl]-
• [2-[(4-Chlorophenyl)(pyridin-2-yl)methoxy]ethyl]dimethylamine

Carbinoxamine Maleate

CAS: 3505-38-2 486-16-8

• Formula: C₁₆H₁₉ClN₂O·C₄H₄O₄
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 406.86

{2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}dimethylamine maleate

CAS: 486-16-8

• Formula: C₁₆H₁₉ClN₂O
• Purity: 95%
• Molecular weight: 290.7879

Carbinoxamine

CAS: 486-16-8

Carbinoxamine: antihistamine for hay fever, angioedema, rhinitis, mild urticaria, dermatographism, allergic conjunctivitis; an H1-antagonist.

• Formula: C₁₆H₁₉ClN₂O
• Purity: 98%
• Color and Shape: Liquid
• Molecular weight: 290.79

2-((4-Chlorophenyl)(pyridin-2-yl)methoxy)-N,N-dimethylethanamine

CAS: 486-16-8

2-((4-Chlorophenyl)(pyridin-2-yl)methoxy)-N,N-dimethylethanamine (ZDX) is a new nonsteroidal anti-inflammatory drug that has been developed for the treatment …

• Formula: C₁₆H₁₉N₂OCl
• Purity: Min. 95%
• Molecular weight: 290.79 g/mol