CAS 486-39-5

Coclaurine

Description:

Coclaurine, with the CAS number 486-39-5, is an alkaloid primarily derived from various plant species, particularly those in the family of the Papaveraceae. It is a colorless to pale yellow crystalline compound that exhibits a range of biological activities, including potential anti-inflammatory and analgesic properties. Coclaurine is known for its structural similarity to other alkaloids, which allows it to interact with various biological targets, including neurotransmitter receptors. The compound is soluble in organic solvents but has limited solubility in water, which influences its bioavailability and pharmacokinetics. In terms of safety, like many alkaloids, coclaurine should be handled with care, as it may exhibit toxicity at certain concentrations. Its potential therapeutic applications are still under investigation, and ongoing research aims to elucidate its mechanisms of action and efficacy in various medical contexts. Overall, coclaurine represents a fascinating subject of study within the field of natural products and pharmacology.

Formula: C₁₇H₁₉NO₃

InChI: InChI=1/C17H19NO3/c1-21-17-9-12-6-7-18-15(14(12)10-16(17)20)8-11-2-4-13(19)5-3-11/h2-5,9-10,15,18-20H,6-8H2,1H3/t15-/m1/s1

InChI key: InChIKey=LVVKXRQZSRUVPY-HNNXBMFYSA-N

SMILES: C([C@H]1C=2C(=CC(OC)=C(O)C2)CCN1)C3=CC=C(O)C=C3

Synonyms:

• (-)-Coclaurine
• (1S)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-7-isoquinolinol
• (S)-1,2,3,4-Tetrahydro-1-(p-hydroxybenzyl)-6-methoxy-7-isoquinolinol
• (S)-1-(p-Hydroxybenzyl)-6-methoxy-7-hydroxy-1,2,3,4-tetrahydroisoquinoline
• (S)-Coclaurine
• 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-((4-hydroxyphenyl)methyl)-6-methoxy-, (R)-
• 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-, (1R)-
• 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-, (1S)-
• 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-, (S)-
• Coclaurin
• Machiline
• Caclaurine
• (RS)-coclaurine
• (S)-1-(4-Hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-7-ol
• [S,(+)]-1,2,3,4-Tetrahydro-1-(4-hydroxybenzyl)-6-methoxyisoquinolin-7-ol
• (S)-colaurine
• (1S)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxyisoquinolin-7-ol

Coclaurine

CAS: 486-39-5

Formula: C₁₇H₁₉NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 285.3377

Ref: IN-DA006WP5

(S)-Coclaurine

CAS: 486-39-5

(S)-Coclaurine (Coclaurine) is an antagonist of nAChR isolated from Sarcopetalum harveyanum.

Formula: C₁₇H₁₉NO₃

Purity: 97.72%

Color and Shape: Solid

Molecular weight: 285.34

Ref: TM-TN1519

Coclaurine

CAS: 486-39-5

Formula: C₁₇H₁₉NO₃

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 285.343

Ref: BP-SBP01525

Coclaurine

CAS: 486-39-5

Coclaurine is a benzylisoquinoline alkaloid, which is primarily derived from certain plant species belonging to families such as Annonaceae and Lauraceae. As a secondary metabolite, coclaurine is synthesized in plants and contributes to their chemical defense mechanisms. The mode of action of coclaurine involves interaction with various biological targets, including enzymes and receptors, often influencing neurotransmission and exhibiting antioxidative properties.

Formula: C₁₇H₁₉NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 285.34 g/mol

Ref: 3D-AAA48639