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CAS 4862-94-6

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4-amino-N-(2-hydroxyethyl)benzenesulfonamide

Description:
4-Amino-N-(2-hydroxyethyl)benzenesulfonamide, also known as sulfanilamide, is an organic compound characterized by its sulfonamide functional group, which is a sulfonic acid derivative containing an amine. This compound features an amino group (-NH2) and a hydroxyethyl group (-CH2CH2OH) attached to a benzene ring, contributing to its solubility in water and polar solvents. It typically appears as a white to off-white crystalline solid. The presence of the sulfonamide group imparts antibacterial properties, making it relevant in medicinal chemistry, particularly in the development of sulfa drugs. The compound is known for its ability to inhibit bacterial growth by interfering with folic acid synthesis. Its melting point, solubility, and stability can vary based on environmental conditions, but it is generally stable under standard laboratory conditions. Safety data indicates that it should be handled with care, as it may cause irritation upon contact with skin or eyes. Overall, 4-amino-N-(2-hydroxyethyl)benzenesulfonamide is significant in both pharmaceutical applications and chemical research.
Formula:C8H12N2O3S
InChI:InChI=1/C8H12N2O3S/c9-7-1-3-8(4-2-7)14(12,13)10-5-6-11/h1-4,10-11H,5-6,9H2
SMILES:c1cc(ccc1N)S(=O)(=O)NCCO
Synonyms:
  • Benzenesulfonamide, 4-amino-N-(2-hydroxyethyl)-
  • 4-Amino-N-(2-hydroxyethyl)benzenesulfonamide
  • N-(2-hydroxyethyl)-4-aminobenzene sulfonamide
  • 4-Amino-N-(2-hydroxyethyl)benzenesulphonamide
  • 2-(4-AMINOPHENYLSULFONAMIDO)ETHANOL
  • 4-[(2-Hydroxyethyl)sulphamoyl]aniline
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