![[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-(R)-benzenebutanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F19813-boc-r-3-amino-4-245-trifluoro-phenyl-butyric-acid.webp&w=3840&q=75)
CAS 486460-00-8
:[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-(R)-benzenebutanoic acid
Description:
The chemical substance known as "[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-(R)-benzenebutanoic acid," with the CAS number 486460-00-8, is a complex organic compound characterized by its unique functional groups and structural features. It contains an amino group, a carboxylic acid, and a trifluoromethyl group, which contribute to its reactivity and potential applications in medicinal chemistry. The presence of the 1,1-dimethylethoxycarbonyl moiety suggests that it may serve as a protecting group in synthetic pathways. The trifluoromethyl substituents enhance lipophilicity and may influence biological activity, making this compound of interest in drug design. Additionally, the chirality indicated by the (R) configuration suggests that the compound may exhibit stereospecific properties, which can be crucial for its interaction with biological targets. Overall, this compound's distinct characteristics make it a valuable subject for research in organic synthesis and pharmaceutical development.
Formula:C15H18F3NO4
InChI:InChI=1/C15H18F3NO4/c1-15(2,3)23-14(22)19-9(6-13(20)21)4-8-5-11(17)12(18)7-10(8)16/h5,7,9H,4,6H2,1-3H3,(H,19,22)(H,20,21)/t9-/m1/s1
SMILES:CC(C)(C)OC(=N[C@H](Cc1cc(c(cc1F)F)F)CC(=O)O)O
Synonyms:- Boc-(R)-3-Amino-4-(2,4,5-Trifluorophenyl)-butyric acid
- (3R)-N-(Tert-Butoxycarbonyl)-3-Amino-4-(2,4,5-Trifluorophenyl)Butanoic Acid
- (3R)-3-(1,1-Dimethylethoxy Carbonyl) Amino]-4-(2,4,5-Trifluorophenyl) Butanoic Acid
- Boc-(R)-3-Amino-4-(2,4,5-Trifluorophenyl)Butanoic Acid
- (R)-Boc-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
- (R)-N-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
- (3R)-3-[(tert-butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid
- Benzenebutanoic acid,3-[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-, (3R)-
- Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid
- (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid
- (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid
- (R)-3-(tert-butoxy carbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid
- 3(R)-tert-Butoxycarbonylamino-4-(2,4,5-trifluoro-phenyl)-butyric acid
- (R)-3-[(Tert-Butoxycarbonyl)amino]-4-(2,4,5-Trifluoro Phenyl)butanoic Acid
- (Tert-Butoxy)Carbonyl (R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid
- 5-TRIFLUORO-PHENYL)-BUTYRIC ACID
- Sitagliptin interMediate
- (3R)-N-Boc-3-amin
- Boc-(R)-3-Amino-4-(2,4,5-Trifluorophenyl)Butanoic Acid / Sitagliptin Intermediate
- Parecoxib SodiuM API
- (3R)-3-{[(tert-butoxy)carbonyl]amino}-4-(2,4,5-trifluorophenyl)butanoic acid
- N-Boc Sitagliptin Acid Impurity
- Sitagliptin EP Impurity 15
- (R)-3-(Tert-Butoxycarbonyl)-4-(2,4,5-Trifluorophenyl)Butanoic Acid
- (R)-N-Boc-3-AMino-4-(2,4,5-trifluorophenyl)butanoic 
- Sitagliptin N-BOC Carboxylic Acid
- Sitagliptin Impurity 19
- Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,(bR)-
- (3R)-N-(TERT-BUTOXYCARBONYL)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BU
- [[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-(R)-be...
- Sitagliptin Intermediate 1
- Sitagliptin interMediateB
- Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid (3R)-N-(tert-Butoxycarbonyl)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
- Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-ButyricAci
- (βR)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,4,5-trifluorobenzenebutanoic acid
- [[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-(R)-benzenebuta
- Sitagliptin Acid Boc Impurity (Impurity A)
- BOC-(R-)3-Amino-4(2,4,5-triflurophenyl)Butanoic acid
- BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID ISO 9001：2015 REACH
- (3R)-N-(tert-Butoxycarbonyl)-3-amino-4-(2,4,5-trifluoro phenyl)butanoic acid [Sita Acid]
- butanoic acid (BOC acid)
- (R)-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacid
- Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (Boc acid)
- (3R)-N-(tert-Butoxycarbonyl)-3-aMino-4-(2,4,5-trifluorophenyl)-butanoic acid- Boc-(R)-3-AMino-4-(2,4,5-trifluorophenyl)
- Benzenebutanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-, (βR)-
- Sitagliptin Impurity 78
- BOC-(R)-3-AMINO-4-(2
- (R)-Sitagliptin N-Boc-Acid IMpurity
- [[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-(R)-benzenebutanoic acid
- (3R)-3-((1,1-DIMETHYLETHOXYCARBONYL)AMINO)-4-(2,4,5-TRIFLUROPHENYL)-BUTANOIC ACID
- 4-(6-{[(tert-butoxy)carbonyl]aMino}-1,2,5-trifluorocyclohexa-2,4-dien-1-yl)butanoic acid
- Boc-(R)-3-Amino-4-(2,4,5-trifluorphenyl)butanoic acid
- SITAGLIPTIN CAS 654671-78-0 INTERMEDIATES
- BOC- Butanoic Acid
- Sitagliptin N-BOC Carboxylic acid Impurity
- (3R)-N-Boc-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
- Sitagliptin Imp-1(sitagliptin Impurity-A)
- Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid, >=99%
- BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENY
- Sitagliptin Impurity 19 ((R)-Sitagliptin N-Boc-Acid Impurity)
- (R)-3-(Boc-aMino)-4-(2,4,5-trifluorophenyl)butanoic acid
- (3R) - N - (tert butoxycarbonyl) -3-amino-4- (2,4,5-trifluorophenyl) butyric acid
- See more synonyms
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Found 8 products.
(3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:Formula:C15H18F3NO4Purity:97%Color and Shape:SolidMolecular weight:333.3029Sitagliptin Impurity 19 ((R)-Sitagliptin N-Boc-Acid Impurity)
CAS:Formula:C15H18F3NO4Color and Shape:White To Off-White SolidMolecular weight:333.31(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acidPurity:98%Molecular weight:333.306g/mol(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid
CAS:Controlled Product<p>Applications (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid has been used as a reactant for the preparation of dipeptidyl peptidase-4 (DPP4) inhibitors for the treatment of type 2 diabetes, such as sitagliptin.<br>References Kim, H.J., et. al.: Bioorg. Med. Chem. Lett., 22, 5545 (2012)<br></p>Formula:C15H18F3NO4Color and Shape:NeatMolecular weight:333.30(R)-N-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:Formula:C15H18F3NO4Purity:95%Color and Shape:SolidMolecular weight:333.307Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:<p>Intermediate in the synthesis of sitagliptin</p>Formula:C15H18F3NO4Purity:Min. 95%Molecular weight:333.3 g/mol
![(3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0038OZ.jpg&w=3840&q=75)
![(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FPC99712.jpg&w=3840&q=75)
