CAS: 486460-32-6 - Sitagliptin

Formula: C₁₆H₁₅F₆N₅O

InChI: InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1

InChI key: InChIKey=MFFMDFFZMYYVKS-SECBINFHSA-N

SMILES: O=C(N1CC2=NN=C(N2CC1)C(F)(F)F)CC(N)CC3=CC(F)=C(F)C=C3F

Synonyms:

• (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine
• (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
• (3R)-3-Amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
• (3R)-3-Amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
• (3R)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone
• (3S)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
• 1,2,4-Triazolo(4,3-a)pyrazine, 7-((3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl)-5,6,7,8-tetrahydor-3-(trifluoromethyl)-
• 1,2,4-Triazolo[4,3-a]pyrazine, 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-
• 1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (3R)-
• 3(R)-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
• 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine
• Ristaben
• Sitagliptin Base
• Sitagliptin Intermediate
• Sitagliptin free base
• Sitagliptine
• Tesavel
• Xelevia
• Sitagliptin

Sitagliptin

CAS: 486460-32-6

Sitagliptin (MK0431), an oral DPP-4 inhibitor, treats type 2 diabetes alone or with metformin/thiazolidinedione by …

• Formula: C₁₆H₁₅F₆N₅O
• Purity: 99.33% - 99.4%
• Color and Shape: Yellow Grease
• Molecular weight: 407.31

Sitagliptin

CAS: 486459-71-6 486460-32-6

• Formula: C₁₆H₁₅F₆N₅O
• Color and Shape: White To Off-White Solid
• Molecular weight: 407.32

Sitagliptin

CAS: 486460-32-6

• Formula: C₁₆H₁₅F₆N₅O
• Color and Shape: Neat
• Molecular weight: 407.31

Sitagliptin 100 µg/mL in Acetonitrile

CAS: 486460-32-6

• Formula: C₁₆H₁₅F₆N₅O
• Color and Shape: Single Solution
• Molecular weight: 407.31

Sitagliptin HCl

CAS: 486459-71-6 486460-32-6

• Formula: C₁₆H₁₅F₆N₅O·HCl
• Molecular weight: 407.32 36.46

Sitagliptin

CAS: 486460-32-6

• Formula: C₁₆H₁₅F₆N₅O
• Purity: ≥ 98.0%
• Color and Shape: White to off-white or yellow-beige powder
• Molecular weight: 407.31

Sitagliptin-d4

CAS: 1432063-88-1 486460-32-6

• Formula: C₁₆H₁₁F₆N₅OD₄
• Molecular weight: 411.35

Sitagliptin Impurity 103

CAS: 486459-71-6 486460-32-6

• Formula: C₆H₉ClN₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 172.62

Sitagliptin

CAS: 486460-32-6

Applications Sitagliptin (cas# 486460-32-6) is a useful research chemical.

• Formula: C₁₆H₁₅F₆N₅O
• Color and Shape: Off-White
• Molecular weight: 407.31

(3R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one

CAS: 486460-32-6

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 407.32000732421875

Sitagliptin

CAS: 486460-32-6

Inhibitor of dipeptidyl-peptidase; anti-diabetic agent

• Formula: C₁₆H₁₅F₆N₅O
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 407.31 g/mol

5-Desfluoro-destrifluoromethyl Sitagliptin Hydrochloride Salt

CAS: 486460-32-6

• Formula: C₁₅H₁₇F₂N₅O·HCl
• Color and Shape: Neat
• Molecular weight: 357.786

4-Desfluoro-destrifluoromethyl Sitagliptin Hydrochloride Salt

CAS: 486460-32-6

• Formula: C₁₅H₁₇F₂N₅O·HCl
• Color and Shape: Neat
• Molecular weight: 357.786