CAS 487-90-1

Porphobilinogen

Description:

Porphobilinogen is a key intermediate in the biosynthesis of heme, an essential component of hemoglobin and various enzymes. It is a colorless, water-soluble compound with the molecular formula C₁₄H₁₅N₃O. Porphobilinogen is characterized by its pyrrole rings, which are fundamental to its structure and function. It is produced from the condensation of two molecules of aminolevulinic acid (ALA) in the presence of the enzyme porphobilinogen synthase. This compound plays a crucial role in the metabolic pathway leading to the formation of porphyrins, which are vital for oxygen transport and various biochemical processes. Porphobilinogen is sensitive to light and can undergo oxidation, leading to the formation of more complex porphyrin structures. Its significance extends beyond basic biochemistry, as abnormalities in its metabolism can lead to disorders such as porphyria, which are characterized by the accumulation of porphyrins and their precursors. Overall, porphobilinogen is a pivotal molecule in the synthesis of heme and related compounds, highlighting its importance in both health and disease.

Formula: C₁₀H₁₄N₂O₄

InChI: InChI=1/C10H14N2O4/c11-4-8-7(3-10(15)16)6(5-12-8)1-2-9(13)14/h5,12H,1-4,11H2,(H,13,14)(H,15,16)

InChI key: InChIKey=QSHWIQZFGQKFMA-UHFFFAOYSA-N

SMILES: C(C(O)=O)C=1C(CCC(O)=O)=CNC1CN

Synonyms:

• 1H-Pyrrole-3-propanoic acid, 5-(aminomethyl)-4-(carboxymethyl)-
• 3-[5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid hydrate
• 3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid
• 5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propanoic acid
• Porphobilinogen
• Pyrrole-3-propionic acid, 5-(aminomethyl)-4-(carboxymethyl)-
• PBG
• 5-(Aminomethyl)-4-(carboxymethyl)pyrrole-3-propionic acid
• porphobilinogen (synth.)
• 5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid
• 3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propionic acid

3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid hydrate

CAS: 487-90-1

Formula: C₁₀H₁₄N₂O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 226.2292

Ref: IN-DA003TUW

Porphobilinogen

CAS: 487-90-1

Formula: C₁₀H₁₄N₂O₄

Purity: ≥ 97.0%

Color and Shape: White to pink, beige or orange powder

Molecular weight: 226.23

Ref: 7W-GK7307

Porphobilinogen

CAS: 487-90-1

Formula: C₁₀H₁₄N₂O₄

Purity: >97%

Molecular weight: 244.24

Ref: FT-P226

Porphobilinogen-13C3

CAS: 487-90-1

Formula: C₁₀H₁₄N₂O₄

Molecular weight: 229.20

Ref: 4Z-P-238002

Porphobilinogen-13C2-15N

CAS: 487-90-1

Formula: C₈₁₃C₂H₁₄N₁₅NO₄

Molecular weight: 229.21

Ref: 4Z-P-238003

Porphobilinogen

CAS: 487-90-1

Formula: C₁₀H₁₄N₂O₄

Molecular weight: 226.23

Ref: 4Z-P-238001

Porphobilinogen-d4

CAS: 487-90-1

Formula: C₁₀H₁₀D₄N₂O₄

Molecular weight: 230.26

Ref: 4Z-P-238004

Porphobilinogen

Controlled Product

CAS: 487-90-1

Applications An intermediate in the biosynthesis of Heme, found in the urine of patients with acute porphyria.
References Westall, et al.: Nature, 170, 614 (1952), Cookson, R., et al.: Biochem, J., 57, 476 (1954), MacDonald, J., Can. J. Chem., 35, 715 (1957),

Formula: C₁₀H₁₄N₂O₄

Color and Shape: Neat

Molecular weight: 226.23

Ref: TR-P689500

Porphobilinogen-13C2,15N

CAS: 487-90-1

Applications Porphobilinogen-13C315N is the labeled compound of Porphobilinogen(P689500). Porphobilinogen is an intermediate in the biosynthesis of Heme, found in the urine of patients with acute porphyria.
References Westall, et al.: Nature, 170, 614 (1952), Cookson, R., et al.: Biochem, J., 57, 476 (1954), MacDonald, J., Can. J. Chem., 35, 715 (1957),

Formula: C₂C₈H₁₄₁₅NNO₄

Color and Shape: Neat

Molecular weight: 229.208

Ref: TR-P689504

Porphobilinogen

CAS: 487-90-1

Porphobilinogen act as a phytotoxin, a metabotoxin, and a neurotoxin.

Formula: C₁₀H₁₄N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 226.23

Ref: TM-T19130