CAS 488-69-7

Fructose 1,6-bisphosphate

Description:

Fructose 1,6-bisphosphate (FBP) is a crucial intermediate in the glycolytic pathway, playing a significant role in cellular metabolism. It is a phosphorylated sugar, specifically a hexose, derived from fructose. The compound features two phosphate groups attached to the first and sixth carbon atoms, which are essential for its function in energy production. FBP is a colorless, water-soluble compound, and its structure allows it to participate in various enzymatic reactions, particularly those catalyzed by aldolase and fructose-1,6-bisphosphatase. It acts as an allosteric regulator, influencing the activity of key enzymes in metabolic pathways, thereby playing a role in the regulation of gluconeogenesis and glycolysis. The presence of the phosphate groups contributes to its high-energy characteristics, making it a vital molecule in energy transfer processes within cells. Additionally, FBP is involved in the regulation of metabolic flux and is a key player in the balance between energy production and consumption in living organisms.

Formula: C₆H₁₄O₁₂P₂

InChI: InChI=1S/C6H14O12P2/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16/h3,5-7,9-10H,1-2H2,(H2,11,12,13)(H2,14,15,16)/t3-,5-,6-/m1/s1

InChI key: InChIKey=XPYBSIWDXQFNMH-UYFOZJQFSA-N

SMILES: [C@H]([C@@H](C(COP(=O)(O)O)=O)O)([C@@H](COP(=O)(O)O)O)O

Synonyms:

• 1,6-Bis(dihydrogenophosphate) de D-fructose
• 1,6-bis(dihidrogenofosfato) de D-fructosa
• 1,6-di-O-phosphono-D-fructofuranose
• 1,6-di-O-phosphono-D-fructose
• 1,6-di-O-phosphono-beta-D-fructofuranose
• 1,6-di-O-phosphonohex-2-ulofuranose
• 2,5-anhydro-1,6-di-O-phosphono-D-glucitol
• <span class="text-smallcaps">D</span>-Fructose 1,6-biphosphate
• <span class="text-smallcaps">D</span>-Fructose 1,6-bisphosphate
• <span class="text-smallcaps">D</span>-Fructose 1,6-diphosphate
• <span class="text-smallcaps">D</span>-Fructose, 1,6-bis(dihydrogen phosphate)
• D-Fructose 1,6-biphosphate
• D-Fructose 2,6-Diphosphate Di-Sodium Salt
• D-Fructose-1,6-bis(dihydrogenphosphat)
• D-fructose 1,6-bis(dihydrogen phosphate)
• D-fructose 1,6-bisphosphate
• Diphosphofructose
• Esafosfan
• Esafosfina
• F1,6diP
• FDP
• Fosfructose
• Fructose 1,6-bis(dihydrogen phosphate)
• Fructose 1,6-diphosphate
• Fructose Diphosphate
• Fructose, 1,6-bis(dihydrogen phosphate), <span class="text-smallcaps">D</span>-
• Fructose, 1,6-bis(dihydrogen phosphate), D-
• Fructose-1,6-Bisphosphate
• Harden-Young ester
• beta-D-fructofuranose-1,6-diphosphate

{[(3S,4S,5R)-2,3,4-trihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]methoxy}phosphonic acid

CAS: 488-69-7

Formula: C₆H₁₄O₁₂P₂

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 340.1157

Ref: IN-DA00393R

Fosfructose

CAS: 488-69-7

Fosfructose

Purity: ≥98%

Molecular weight: 340.12g/mol

Ref: 54-BUP08165

D-Fructose 1,6-diphosphate

CAS: 488-69-7

Formula: C₆H₁₁O₁₂P₂

Molecular weight: 340.12

Ref: 7W-GC1231

D-Fructose-1,6-diphosphate

CAS: 488-69-7

D-Fructose-1,6-diphosphate

Formula: C₆H₁₄O₁₂P₂

Purity: 95%

Color and Shape: cream solid

Molecular weight: 340.12g/mol

Ref: 54-OR918472

Fosfructose

CAS: 488-69-7

D-fructose-1,6-diphosphate (D-fructose-1,6-diphosphate), also known as Fosfructose, is a cytoprotective natural sugar phosphate.

Formula: C₆H₁₄O₁₂P₂

Purity: 99.84%

Color and Shape: Solid

Molecular weight: 340.12

Ref: TM-T3228

D-Fructose-13C6 1,6-Bisphosphate Sodium Salt Hydrate

Controlled Product

CAS: 488-69-7

Applications Isotope labelled Fructose1,6-bisphosphate is an intermediate that lies within the glycolysis metabolic pathway and is also an allosteric activator of pyruvate kinase.
References Hinder, L.M., et al.: J. Endocriol., 216, 1 (2013); Takubo, K., et al.: Cell. Stem. Cell., 12, 49 (2013); Kalam, Y., et al.: Clin. Toxciol., 50, 546 (2012);

Formula: C₆H₁₄O₁₂P₂•xH₂O•xNa

Color and Shape: Neat

Molecular weight: 346.06

Ref: TR-F792571

D-Fructose-1,6-diphosphate

CAS: 488-69-7

D-Fructose-1,6-diphosphate is a chemical that is found in the cytosol of cells. It is an intermediate in the metabolism of fructose and also has an important role in the synthesis of fatty acids and phospholipids. D-Fructose-1,6-diphosphate is an effective inhibitor of sodium succinate dehydrogenase, which converts succinate to fumarate. D-Fructose-1,6-diphosphate has a neutral pH profile and is not affected by changes in pH levels. The optimum pH for this compound is between 6.5 and 7.5. D-Fructose-1,6-diphosphate binds to proteins with unsaturated alkyl chains such as creatine kinase and glutamate dehydrogenase. It has been shown to have hemolytic effects on erythrocytes (red blood cells) at high concentrations, which may be due to its ability to bind

Formula: C₆H₁₄O₁₂P₂

Purity: (¹H-Nmr) Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 340.12 g/mol

Ref: 3D-MF10066

D-FRUCTOFURANOSE 1,6-BISPHOSPHATE

CAS: 488-69-7

Formula: C₆H₁₄O₁₂P₂

Purity: ≥98.0%

Color and Shape: Liquid, No data available.

Molecular weight: 339.996

Ref: 10-F533431

D-Fructose-2-13C2 1,6-Bisphosphate Tetrasodium Salt Hydrate

Controlled Product

CAS: 488-69-7

Applications Isotope labelled Fructose1,6-bisphosphate is an intermediate that lies within the glycolysis metabolic pathway and is also an allosteric activator of pyruvate kinase.
References Hinder, L.M., et al.: J. Endocriol., 216, 1 (2013); Takubo, K., et al.: Cell. Stem. Cell., 12, 49 (2013); Kalam, Y., et al.: Clin. Toxciol., 50, 546 (2012);

Formula: C₅₁₃CH₁₀Na₄O₁₂P₂•xH₂O

Color and Shape: Neat

Molecular weight: 429.03

Ref: TR-F792572

D-Fructose-13C6-1,6-diphosphate sodium salt

CAS: 488-69-7

D-Fructose-13C6-1,6-diphosphate sodium salt is a reactive compound used as a model in studies of metabolic disorders. It has been shown to have an inhibitory effect on the enzymes that catalyze the conversion of D-fructose 1,6 diphosphate to D-fructose 6 phosphate in the cytosol. The compound is also useful for determining the binding of calcium ions to proteins and for measuring the activity of carbon source enzymes.

Formula: C₆H₁₀Na₄O₁₂P₂·xH₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 434 g/mol

Ref: 3D-OF73260