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CAS 488820-34-4

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9-(AMinoMethyl)Minocycline

Description:
9-(Aminomethyl)minocycline is a derivative of minocycline, which is a broad-spectrum antibiotic belonging to the tetracycline class. This compound features an aminomethyl group at the C9 position of the minocycline structure, which enhances its antibacterial properties and may improve its pharmacokinetic profile. It exhibits characteristics typical of tetracyclines, including the ability to inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit. The compound is effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating various infections. Additionally, it may possess anti-inflammatory properties, which can be beneficial in treating conditions like acne. The presence of the aminomethyl group can also influence its solubility and stability compared to its parent compound. As with other tetracyclines, it is important to consider potential side effects, such as photosensitivity and gastrointestinal disturbances, as well as contraindications in certain populations, such as pregnant women and children due to the risk of tooth discoloration.
Formula:C24H30N4O7
Synonyms:
  • 2-Naphthacenecarboxamide, 9-(aminomethyl)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-
  • OMAD-008
  • 9-(AMinoMethyl)Minocycline
  • GIUWSFUPVNIWAO-DMZCIERTSA-N
  • TigecyclineImpurity29
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