CAS 4891-71-8

(6α,11β,16α)-9-Chloro-6-fluoro-11-hydroxy-16-methyl-21-[(1-oxohexyl)oxy]pregna-1,4-diene-3,20-dione

Description:

The chemical substance known as "(6α,11β,16α)-9-Chloro-6-fluoro-11-hydroxy-16-methyl-21-[(1-oxohexyl)oxy]pregna-1,4-diene-3,20-dione," with the CAS number 4891-71-8, is a synthetic steroid compound. It belongs to the class of corticosteroids, which are characterized by their anti-inflammatory and immunosuppressive properties. This compound features a complex steroid structure, including multiple functional groups such as a chloro group, a fluoro group, and a hydroxy group, which contribute to its biological activity. The presence of the 1-oxohexyl ether moiety suggests potential modifications in its pharmacokinetics and receptor binding affinity. Typically, such compounds are investigated for their therapeutic applications in treating various inflammatory and autoimmune conditions. The specific stereochemistry indicated by the nomenclature suggests that it may exhibit unique interactions with biological targets, influencing its efficacy and safety profile. As with all synthetic steroids, careful consideration of dosage and potential side effects is essential in clinical applications.

Formula: C₂₈H₃₈ClFO₅

InChI: InChI=1S/C28H38ClFO5/c1-5-6-7-8-24(34)35-15-22(32)25-16(2)11-18-19-13-21(30)20-12-17(31)9-10-27(20,4)28(19,29)23(33)14-26(18,25)3/h9-10,12,16,18-19,21,23,25,33H,5-8,11,13-15H2,1-4H3/t16-,18+,19+,21+,23+,25-,26+,27+,28+/m1/s1

InChI key: InChIKey=MMTRTBFDFNRBQO-ANHDKODLSA-N

SMILES: Cl[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@@H](C(COC(CCCCC)=O)=O)[C@H](C)C3)[H])(C[C@H](F)C=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

• (6Alpha,11Beta,16Alpha)-9-Chloro-6-Fluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Hexanoate
• (6α,11β,16α)-9-Chloro-6-fluoro-11-hydroxy-16-methyl-21-[(1-oxohexyl)oxy]pregna-1,4-diene-3,20-dione
• 9-Chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-hexanoate
• Clocortolone caproate
• Clocortolone capronate
• Pregna-1,4-diene-3,20-dione, 9-chloro-6-fluoro-11-hydroxy-16-methyl-21-[(1-oxohexyl)oxy]-, (6α,11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methyl-, 21-hexanoate

Clocortolone Caproate

CAS: 4891-71-8

Formula: C₂₈H₃₈ClFO₅

Color and Shape: White To Off-White Solid

Molecular weight: 509.06

Ref: 4Z-F-071003

Clocortolone caproate

Controlled Product

CAS: 4891-71-8

Clocortolone caproate is a crystalline compound that belongs to the class of steroid hormones. It has a high melting point, and does not dissolve in water. Clocortolone caproate is available commercially as an oil solution. This preparation is used in diagnostic tests, pharmaceutical preparations, and as an active substance in hormone therapy. Clocortolone caproate has been shown to have anti-inflammatory properties and can be used for the treatment of rheumatoid arthritis and other inflammatory diseases. The drug also inhibits the formation of inflammatory prostaglandins by inhibiting cyclooxygenase (COX), which converts arachidonic acid into prostaglandins.

Formula: C₂₈H₃₈ClFO₅

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 509.05 g/mol

Ref: 3D-FC45165

Clocortolone Caproate

Controlled Product

CAS: 4891-71-8

Formula: C₂₈H₃₈ClFO₅

Color and Shape: Neat

Molecular weight: 509.05

Ref: TR-C583815

Clocortolone Caproate

CAS: 4891-71-8

Formula: C₂₈H₃₈ClFO₅

Molecular weight: 509.05

Ref: ST-EA-CP-F56027

Clocortolone hexanoate

CAS: 4891-71-8

Clocortolone hexanoate

Color and Shape: Off-White

Ref: 47-406