CAS 490-78-8

2′,5′-Dihydroxyacetophenone

Description:

2′,5′-Dihydroxyacetophenone, with the CAS number 490-78-8, is an organic compound characterized by its aromatic structure featuring two hydroxyl groups and an acetophenone moiety. This compound typically appears as a white to off-white crystalline solid and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water. The presence of hydroxyl groups contributes to its potential as a phenolic compound, which can exhibit antioxidant properties. It is often utilized in various applications, including as an intermediate in organic synthesis, in the production of dyes, and in the formulation of pharmaceuticals. Additionally, 2′,5′-Dihydroxyacetophenone can participate in various chemical reactions, such as oxidation and esterification, making it a versatile compound in chemical research and industrial applications. Its structural features also allow it to engage in hydrogen bonding, influencing its reactivity and interactions with other substances. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.

Formula: C₈H₈O₃

InChI: InChI=1S/C8H8O3/c1-5(9)7-4-6(10)2-3-8(7)11/h2-4,10-11H,1H3

InChI key: InChIKey=WLDWSGZHNBANIO-UHFFFAOYSA-N

SMILES: C(C)(=O)C1=C(O)C=CC(O)=C1

Synonyms:

• 1-(2,5-Dihydroxyphenyl)Ethanone
• 1-(2,5-Dihydroxyphenyl)ethan-1-one
• 1-Acetyl-2,5-dihydroxybenzene
• 2',5'-Dihydroxy acetophenone
• 2,5-Dihydroxy Acetophenone
• 2,5-Dihydroxy-1-acetylbenzene
• 2,5-Dihydroxyacetophenone
• 2-Acetyl hydroquinone
• 2-Acetyl-1,4-benzenediol
• 2-Acetylhydroquinone
• Acetophenone, 2′,5′-dihydroxy-
• Ethanone, 1-(2,5-dihydroxyphenyl)-
• NSC 3759

2',5'-Dihydroxyacetophenone

CAS: 490-78-8

Formula: C₈H₈O₃

Purity: >98.0%(GC)

Color and Shape: Light orange to Yellow to Green powder to crystal

Molecular weight: 152.15

Ref: 3B-D1955

2',5'-Dihydroxyacetophenone, 98+%

CAS: 490-78-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₈O₃

Purity: 98+%

Color and Shape: Powder, Yellow to green

Molecular weight: 152.15

Ref: 02-A12185

1-(2,5-Dihydroxyphenyl)ethanone

CAS: 490-78-8

Formula: C₈H₈O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 152.1473

Ref: IN-DA00330E

2',5'-Dihydroxyacetophenone

CAS: 490-78-8

2',5'-Dihydroxyacetophenone

Formula: C₈H₈O₃

Purity: 98%

Color and Shape: yellow crystalline powder

Molecular weight: 152.15g/mol

Ref: 54-OR01582

2'',5''-Dihydroxyacetophenone

CAS: 490-78-8

Formula: C₈H₈O₃

Molecular weight: 152.15

Ref: 7W-GK5040

2,5-Dihydroxyacetophenone

CAS: 490-78-8

2,5-Dihydroxyacetophenone

Purity: ≥98%

Molecular weight: 152.15g/mol

Ref: 54-BUP14633

2,5-Dihydroxyacetophenone

CAS: 490-78-8

2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.

Formula: C₈H₈O₃

Purity: 99.75%

Color and Shape: Yellow Powder

Molecular weight: 152.15

Ref: TM-TCS2170

2,5-Dihydroxyacetophenone

CAS: 490-78-8

2,5-Dihydroxyacetophenone (2,5-DA) is a natural phenolic compound that is found in many plants. It has been shown to have anti-inflammatory properties through its ability to inhibit the production of pro-inflammatory cytokines, such as tumor necrosis factor alpha and interleukin 1 beta. 2,5-DA inhibits the formation of reactive oxygen species and nitric oxide in rat neutrophils. 2,5-DA also has the ability to reduce oxidative stress by scavenging free radicals and inhibiting lipid peroxidation. The underlying mechanism for these effects is not fully understood but may be due to its ability to act as a substrate for matrix-assisted laser desorption ionization (MALDI). This means that it can react with protocatechuic acid molecules that are present in the sample preparation chamber, leading to polymerase chain reaction (PCR) amplification. MALDI uses lasers to ablate or vaporize samples

Formula: C₈H₈O₃

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 152.15 g/mol

Ref: 3D-FD36336

2′,5′-Dihydroxyacetophenone

CAS: 490-78-8

Formula: C₈H₈O₃

Purity: 95%

Color and Shape: Crystalline

Molecular weight: 152.149

Ref: 10-F079189

2,5-Dihydroxyacetophenone extrapure, 99%

CAS: 490-78-8

Formula: C₈H₈O₃

Purity: min. 99%

Color and Shape: Yellow, Crystalline powder, Clear

Molecular weight: 152.15

Ref: SR-41384

1-(2,5-Dihydroxyphenyl)ethanone

Controlled Product

CAS: 490-78-8

Applications 1-(2,5-Dihydroxyphenyl)ethanone is an intermediate used in various synthetic preparations of pharmaceutical goods, 1-(2,5-Dihydroxyphenyl)ethanone was untilized in the synthesis of new flavonoid fatty acid esters with anti-adipogenic and glucose consumption enhancing activities.
References Zhao, W., et al.: Bioorg. Med. Chem., 19, 3192 (2011); Jayashree, B.S., et al.: Asian. J. Chem., 22, 1055 (2010); Benites, J., et al.: Bioorg. Med. Chem., 16, 862 (2008);

Formula: C₈H₈O₃

Color and Shape: Neat

Molecular weight: 152.15

Ref: TR-D454450