CAS 491-97-4

Thymidine 5′-(trihydrogen diphosphate)

Description:

Thymidine 5′-(trihydrogen diphosphate), commonly referred to as thymidine triphosphate (dTTP), is a nucleotide that plays a crucial role in cellular metabolism and DNA synthesis. It consists of a thymine base, a deoxyribose sugar, and three phosphate groups. The presence of the triphosphate moiety makes dTTP a high-energy molecule, essential for the polymerization of DNA during replication and repair processes. dTTP is incorporated into the growing DNA strand by DNA polymerases, serving as a building block for nucleic acid synthesis. In addition to its role in DNA synthesis, dTTP is involved in various biochemical pathways, including energy transfer and signaling. The compound is typically found in a hydrated form and is soluble in water, facilitating its participation in enzymatic reactions. Its CAS number, 491-97-4, is used for identification in chemical databases. Overall, dTTP is vital for maintaining genetic integrity and supporting cellular functions in all living organisms.

Formula: C₁₀H₁₆N₂O₁₁P₂

InChI: InChI=1S/C10H16N2O11P2/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(22-8)4-21-25(19,20)23-24(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,19,20)(H,11,14,15)(H2,16,17,18)/t6-,7+,8+/m0/s1

InChI key: InChIKey=UJLXYODCHAELLY-XLPZGREQSA-N

SMILES: O=C1N([C@@H]2O[C@H](COP(OP(=O)(O)O)(=O)O)[C@@H](O)C2)C=C(C)C(=O)N1

Synonyms:

• Thymidine 5′-pyrophosphate
• Thymidine diphosphate
• Thymidine 5′-(trihydrogen pyrophosphate)
• Thymidine pyrophosphate
• Thymidine 5′-(trihydrogen diphosphate)

Thymidine 5′-diphosphate

CAS: 491-97-4

Thymidine 5′-diphosphate (dTDP), a crucial product of pyrimidine synthesis in organisms, is synthesized through the thymidylate kinase (TMPK)-catalyzed

Formula: C₁₀H₁₆N₂O₁₁P₂

Color and Shape: Solid

Molecular weight: 402.19

Ref: TM-T73980