CAS 4914-30-1

dehydroemetine

Description:

Dehydroemetine is a chemical compound derived from the alkaloid emetine, which is primarily obtained from the plant *Cephaelis ipecacuanha*. It is characterized by its molecular formula, which reflects its structure as a complex organic molecule. Dehydroemetine exhibits antiprotozoal properties, making it particularly significant in the treatment of amoebic dysentery caused by *Entamoeba histolytica*. The compound functions by inhibiting protein synthesis in the target organism, thereby exerting its therapeutic effects. In terms of physical properties, dehydroemetine is typically a white to off-white crystalline powder, which is soluble in organic solvents but has limited solubility in water. Its pharmacological profile includes potential side effects, such as gastrointestinal disturbances and cardiovascular effects, necessitating careful dosage and monitoring during use. Due to its potent activity and specific application, dehydroemetine remains an important compound in the field of medicinal chemistry and pharmacology, particularly in regions where amoebic infections are prevalent.

Formula: C₂₉H₃₈N₂O₄

InChI: InChI=1/C29H38N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,24-25,30H,6-12,17H2,1-5H3/t24-,25+/m1/s1

InChI key: InChIKey=XXLZPUYGHQWHRN-RPBOFIJWSA-N

SMILES: C(C=1C[C@]2(C=3C(=CC(OC)=C(OC)C3)CCN2CC1CC)[H])[C@@H]4C=5C(=CC(OC)=C(OC)C5)CCN4

Synonyms:

• (-)-2,3-Dehydroemetine
• (11bS)-3-Ethyl-1,6,7,11b-tetrahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-4H-benzo[a]quinolizine
• 2,3-Didehydro-6',7',10,11-tetramethoxyemetan
• 2,3-Didehydroemetine
• 2-Dehydroemetine
• 3-Ethyl-9,10-dimethoxy-1,6,7,11b-tetrahydro-2-((1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolyl)methyl)-4H-benzo(a)quinolizine
• 4H-Benzo[a]quinolizine, 3-ethyl-1,6,7,11b-tetrahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-, (11bS)-
• 6',7',10,11-Tetramethoxy-2,3-Didehydroemetan
• Bt 436
• Ccris 4110
• Dehidroemetina
• Dehidroemetina [INN-Spanish]
• Dehydroemetine [INN:BAN:DCF]
• Dehydroemetinum
• Dehydroemetinum [INN-Latin]
• Emetan, 2,3-didehydro-6',7',10,11-tetramethoxy- (9CI)
• Emetan, 2,3-didehydro-6′,7′,10,11-tetramethoxy-
• Emetine, 2,3-dehydro-, (-)-
• Emetine, 2,3-didehydro-
• Emetine, 2-dehydro-
• Emetine, dehydro-
• Mebadin
• Nsc 131546
• Ro 1-9334
• Ro 1-9334/19
• Unii-7S79Qt1T91
• Dehydroemetine
• Dehydroemetine hydrochloride
• Dametin
• (11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-4,6,7,11b-tetrahydro-1H-pyrido[2,1-a]isoquinoline

Dehydroemetine

CAS: 4914-30-1

Dehydroemetine

Purity: ≥98%

Molecular weight: 478.62g/mol

Ref: 54-BUP12493

Dehydroemetine

CAS: 4914-30-1

Dehydroemetine, a synthetic emetine, treats amoebic infections and leishmaniasis, and resists metronidazole amoebiosis.

Formula: C₂₉H₃₈N₂O₄

Purity: 98.68% - 99.68%

Color and Shape: Solid

Molecular weight: 478.62

Ref: TM-T15095