CAS 4914-73-2

6-(methylsulfanyl)-9-pentofuranosyl-9H-purin-2-amine

Description:

6-(Methylsulfanyl)-9-pentofuranosyl-9H-purin-2-amine, with the CAS number 4914-73-2, is a purine derivative that exhibits characteristics typical of nucleosides. This compound features a purine base, specifically adenine, linked to a pentofuranosyl sugar, which is a five-membered sugar ring. The presence of a methylsulfanyl group at the 6-position of the purine ring contributes to its unique chemical properties, potentially influencing its biological activity and solubility. As a nucleoside analog, it may interact with biological systems, particularly in nucleic acid metabolism or as a potential therapeutic agent. The structural modifications, such as the methylsulfanyl group, can affect its stability, reactivity, and interaction with enzymes or receptors. This compound may also exhibit specific pharmacological properties, making it of interest in medicinal chemistry and biochemistry. Overall, its characteristics are defined by its purine structure, sugar moiety, and functional groups, which collectively influence its chemical behavior and potential applications.

Formula: C₁₁H₁₅N₅O₄S

InChI: InChI=1/C11H15N5O4S/c1-21-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)20-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)

SMILES: CSc1c2c([nH]c(=N)n1)n(cn2)C1C(C(C(CO)O1)O)O

2-Amino-6-methythio-9-(β-D-ribofuranosyl)-9H-purine

CAS: 4914-73-2

2-Amino-6-methythio-9-(beta-D-ribofuranosyl)-9H-purine is a Nucleoside Derivative - 6-Modified purine nucleoside; Thio-nucleoside.

Formula: C₁₁H₁₅N₅O₄S

Color and Shape: Solid

Molecular weight: 313.33

Ref: TM-TNU0491

6-Methyl-thio-guanosine

CAS: 4914-73-2

6-Methyl-thio-guanosine is a guanine analog that has been used for the treatment of asthma. It was found to be effective in reducing the number of neutrophils and responsiveness of these cells to stimuli. 6-Methyl-thio-guanosine is able to reduce the number of neutrophils in the airway and decrease the amount of sputum produced by patients with chronic obstructive pulmonary disease. 6-Methyl-thio-guanosine also prevents the release of mediators from these cells, which are important in inflammation. This drug has been shown to have an effect on bronchial epithelial cells, slowing their growth and increasing their ability to resist damage.
6-Methyl-thio-guanosine can be administered by inhalation or orally, through microlenses or expansion devices, or by suctioning bronchial secretions. Treatment may also involve injection directly into lung tissue using a bron

Formula: C₁₁H₁₅N₅O₄S

Purity: Min. 95%

Molecular weight: 313.33 g/mol

Ref: 3D-NM46468