CAS 491833-29-5

N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]octanamide

Description:

N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]octanamide, with CAS number 491833-29-5, is a synthetic organic compound characterized by its complex structure, which includes a benzodioxin moiety and a pyrrolidine group. This compound is typically classified as an amide due to the presence of the octanamide functional group. Its stereochemistry is defined by the (1R,2R) configuration, indicating specific spatial arrangements of its atoms, which can influence its biological activity and interactions. The presence of hydroxyl and amine functional groups suggests potential for hydrogen bonding, which may enhance solubility in polar solvents. This compound may exhibit pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its unique structural features could contribute to specific biological activities, although detailed studies would be necessary to elucidate its mechanisms of action and potential applications. As with many synthetic compounds, safety and handling precautions should be observed due to potential toxicity or reactivity.

Formula: C₂₃H₃₆N₂O₄

InChI: InChI=1S/C23H36N2O4/c1-2-3-4-5-6-9-22(26)24-19(17-25-12-7-8-13-25)23(27)18-10-11-20-21(16-18)29-15-14-28-20/h10-11,16,19,23,27H,2-9,12-15,17H2,1H3,(H,24,26)/t19-,23-/m1/s1

InChI key: InChIKey=FJZZPCZKBUKGGU-AUSIDOKSSA-N

SMILES: [C@@H]([C@@H](CN1CCCC1)NC(CCCCCCC)=O)(O)C=2C=C3C(=CC2)OCCO3

Synonyms:

• Cerdelga
• Octanamide, N-[(1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-
• Genz 99067
• N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-octanamide
• N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]octanamide
• Eliglustat
• GENZ-99067; GENZ99067; GENZ 99067
• GENZ-99067;GENZ99067;GENZ 99067;ELIGLUSTAT TARTRATE;GENZ-112638
• N-[(1r,2r)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide
• Elli Gustast
• pyrrolidinyl)-2-propanyl]octanamide
• CS-1540
• N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-
• Eliglustat(Genz-99067)

Eliglustat

CAS: 491833-29-5

Formula: C₂₃H₃₆N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 404.5429

Ref: IN-DA00DBAK

Eliglustat

CAS: 491833-29-5

Eliglustat

Purity: ≥98%

Molecular weight: 404.54g/mol

Ref: 54-BUP12187

Eliglustat

CAS: 491833-29-5

Color and Shape: Neat

Ref: 86-MM3942.00

Eliglustat

CAS: 491833-29-5

Eliglustat (Genz 99067) is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease.

Formula: C₂₃H₃₆N₂O₄

Purity: 99% - 99.70%

Color and Shape: Solid

Molecular weight: 404.54

Ref: TM-T3663

Eliglustat

CAS: 491833-29-5

Eliglustat is an oral medication used as a substrate reduction therapy for Gaucher disease type 1, which is an inherited lysosomal storage disorder. This product is a small-molecule inhibitor derived via chemical synthesis. Its primary mode of action involves the selective inhibition of glucosylceramide synthase, an enzyme responsible for the first committed step in glycosphingolipid biosynthesis. By reducing the production of glucosylceramide, eliglustat decreases the substrate accumulation that contributes to the pathophysiology of Gaucher disease.

Formula: C₂₃H₃₆N₂O₄

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 404.54 g/mol

Ref: 3D-FD158477

Eliglustat-d15

Controlled Product

CAS: 491833-29-5

Formula: C₂₃H₂₁D₁₅N₂O₄

Color and Shape: Neat

Molecular weight: 419.64

Ref: TR-E508027

Eliglustat

Controlled Product

CAS: 491833-29-5

Applications Eliglustat is a specific and potent inhibitor of glucosylceramide synthase.
References Lukina Elena., et al.: Blood, 116, 893 (2010); McEachern Kerry Anne., et al.: Mol Genet Metab Rep., 91, 259 (2007);

Formula: C₂₃H₃₆N₂O₄

Color and Shape: Neat

Molecular weight: 404.54

Ref: TR-E508030