CAS 491873-45-1

3beta-17-Imino-androst-5-en-3-ol Dimer

Controlled Product

CAS: 491873-45-1

Applications 3β-17-Imino-androst-5-en-3-ol Dimer is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17). Abiraterone is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
References Denis, L., et al.: Cancer, 72, 3888 (1993), Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995), Denmeade, S., et al.: Nat. Rev., 2, 389(2002), Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)

Formula: C₃₈H₅₆N₂O₂

Color and Shape: Neat

Molecular weight: 572.86

Ref: TR-I399800

Abiraterone Impurity 10

CAS: 491873-45-1

Formula: C₃₈H₅₆N₂O₂

Molecular weight: 572.88

Ref: ST-EA-CP-A67052