CAS 492-02-4

(1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one

Description:

The chemical substance with the name "(1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one" and CAS number 492-02-4 is a complex organic compound characterized by its intricate bicyclic structure, which includes multiple fused rings and various functional groups. This compound exhibits chirality, indicated by the specific stereochemistry at the designated carbon centers, which can significantly influence its biological activity and interactions. The presence of nitrogen atoms within the diazocin rings suggests potential pharmacological properties, as nitrogen-containing heterocycles are often associated with bioactive compounds. Additionally, the oxo group and methano bridges contribute to its reactivity and stability. Such compounds may be of interest in medicinal chemistry, particularly in the development of pharmaceuticals, due to their potential therapeutic effects. Overall, the structural complexity and unique features of this substance make it a subject of interest for further research and application in various chemical and biological fields.

Formula: C₂₄H₃₀N₄O₂

InChI: InChI=1S/C24H30N4O2/c29-23-5-1-3-21-19-9-17(13-27(21)23)11-25(15-19)7-8-26-12-18-10-20(16-26)22-4-2-6-24(30)28(22)14-18/h1-6,17-20H,7-16H2/t17-,18-,19+,20+/m0/s1

InChI key: InChIKey=LEXDAVFCJPDCNA-VNTMZGSJSA-N

SMILES: C(CN1C[C@@]2(C=3N(C[C@](C1)(C2)[H])C(=O)C=CC3)[H])N4C[C@@]5(C=6N(C[C@@](C5)(C4)[H])C(=O)C=CC6)[H]

Synonyms:

• 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 3,3′-(1,2-ethanediyl)bis[1,2,3,4,5,6-hexahydro-, (1R,1′R,5S,5′S)-
• Cytisine, ethylenedi-
• 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 3,3′-(1,2-ethanediyl)bis[1,2,3,4,5,6-hexahydro-, [1R-[1α,3(1R*,5S*),5α]]-
• Alternine
• 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 1,2,3,4,5,6-hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-, (1R,5S)-
• 1,2-BisN-cytisinylethane
• Thermopsidine
• (1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one
• CC4 >=98% (HPLC)
• CC4

CC4

CAS: 492-02-4

CC4 is an antimicrobial agent that belongs to the group of antimicrobial peptides. It is a cationic peptide that has been shown to inhibit the growth of bacteria, fungi, and viruses. CC4 has also been shown to have anti-inflammatory properties in mice with autoimmune diseases. CC4 binds to glutamate receptors on the surface of cells and blocks glutamate from binding, preventing activation of the receptor and subsequent cell death. CC4 has also been shown to bind specifically to DNA in vitro assays, which may be related to its ability to prevent mitochondrial functions and enzyme activities by blocking ATP production. CC4 also binds selectively to mitochondria in vivo, suggesting that it may also have therapeutic potential as a treatment for colorectal adenocarcinoma or other cancers caused by mitochondrial dysfunction.

Formula: C₂₄H₃₀N₄O₂

Purity: Min. 95%

Molecular weight: 406.52 g/mol

Ref: 3D-AAA49202

CC4

CAS: 492-02-4

Selective α6β2/α4β2 partial agonist; Ki: 12/26nM (rat); poor α3β4/α7 affinity; stimulates dopamine release; reduces nicotine self-admin in rats.

Formula: C₂₄H₃₀N₄O₂

Color and Shape: Solid

Molecular weight: 406.52

Ref: TM-T37202