CAS 492-27-3
:Kynurenic acid
Description:
Kynurenic acid is an endogenous metabolite of the amino acid tryptophan, primarily involved in the kynurenine pathway. It is characterized by its role as a neuroactive compound, exhibiting various biological activities, including neuroprotective and neuroinflammatory effects. Kynurenic acid is known to act as an antagonist at the NMDA (N-methyl-D-aspartate) receptor, which is significant in modulating excitatory neurotransmission and has implications in neurodegenerative diseases and psychiatric disorders. The substance is soluble in water and exhibits a relatively low molecular weight. Its chemical structure features a pyridine ring and a carboxylic acid group, contributing to its acidic properties. Kynurenic acid has been studied for its potential therapeutic applications, particularly in conditions such as schizophrenia, depression, and neurodegeneration. Additionally, it is found in various biological fluids and tissues, reflecting its physiological relevance. Overall, kynurenic acid serves as an important biomolecule in neuroscience and pharmacology, warranting further investigation into its mechanisms and therapeutic potential.
Formula:C10H7NO3
InChI:InChI=1S/C10H7NO3/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9/h1-5H,(H,11,12)(H,13,14)
InChI key:InChIKey=HCZHHEIFKROPDY-UHFFFAOYSA-N
SMILES:OC=1C2=C(N=C(C(O)=O)C1)C=CC=C2
Synonyms:- 2-Carboxy-4-hydroxyquinoline
- 4-Hydroxy-2-quinolinecarboxylic acid
- 4-Hydroxychinolin-2-carbonsaure
- 4-Hydroxyquinaldic acid
- 4-Hydroxyquinaldinic acid
- 4-Hydroxyquinoline-2-Carboxylic Acid
- Acide 4-Hydroxyquinoleine-2-Carboxylique
- Acido 4-Hidroxiquinolina-2-Carboxilico
- Kynurenic acid
- Nsc 58973
- Quinaldic acid, 4-hydroxy-
- Quinurenic acid
- 4-oxo-1,4-dihydroquinoline-2-carboxylic acid
- 4-Hydroxyquinoline-2-carboxylic acid hydrate
- See more synonyms
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Found 10 products.
Kynurenic Acid
CAS:Formula:C10H7NO3Purity:>98.0%(T)(HPLC)Color and Shape:White to Gray to Brown powder to crystalMolecular weight:189.172-Quinolinecarboxylic acid, 4-hydroxy-
CAS:Formula:C10H7NO3Purity:97%Color and Shape:SolidMolecular weight:189.1675Ref: IN-DA00DZ70
1g68.00€5g122.00€10g198.00€1kgTo inquire25g263.00€100g569.00€500gTo inquire100mg25.00€250mg34.00€4-Hydroxyquinoline-2-Carboxylic Acid
CAS:4-Hydroxyquinoline-2-Carboxylic AcidPurity:99%Molecular weight:189.17g/molKynurenic acid
CAS:Formula:C10H7NO3Purity:≥ 98.0% (anhydrous basis)Color and Shape:Pale yellow to green, or pale brown powderMolecular weight:189.17Kynurenic acid
CAS:<p>Kynurenic acid (Quinurenic acid) is an NMDA, glutamate, α7 nicotinic acetylcholine receptor triple antagonist and GPR35/CXCR8 agonist.</p>Formula:C10H7NO3Purity:99.69%Color and Shape:SolidMolecular weight:189.17Kynurenic Acid
CAS:<p>Applications A product of L-Tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties.<br>References Wejksza, K., et al.: Pharmacol. Rep., 61, 751 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Di Natale, B., et al.: Toxicol. Sci., 115, 89 (2010),<br></p>Formula:C10H7NO3Color and Shape:NeatMolecular weight:189.17Kynurenic acid
CAS:<p>NMDA antagonist; endogenous negative modulator of α7 nicotinic receptors</p>Formula:C10H7NO3Purity:Min. 95%Color and Shape:Slightly Yellow PowderMolecular weight:189.17 g/molKynurenic acid - Bio-X ™
CAS:<p>Kynurenic acid is a metabolic product formed during the breakdown of the amino acid tryptophan. It acts as a neuromodulator in the brain by inhibiting the NMDA receptor, which is involved in nerve cell signaling. While its exact role is still being studied, it's believed to regulate neuronal excitability. Kynurenic acid has been linked to conditions like schizophrenia and epilepsy, though its precise contributions are not fully understood.</p>Formula:C10H7NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:189.17 g/mol
