CAS 492-37-5

2-Phenylpropionic acid

Description:

2-Phenylpropionic acid, with the CAS number 492-37-5, is an aromatic carboxylic acid characterized by its phenyl group attached to a propionic acid backbone. This compound typically appears as a white to off-white crystalline solid and is known for its moderate solubility in water, while being more soluble in organic solvents such as ethanol and ether. It has a melting point that generally falls within a specific range, indicating its solid state at room temperature. The presence of both a carboxylic acid functional group and an aromatic ring contributes to its chemical reactivity, allowing it to participate in various organic reactions, including esterification and amidation. 2-Phenylpropionic acid is also recognized for its potential applications in pharmaceuticals and as a building block in organic synthesis. Additionally, it exhibits anti-inflammatory properties, making it of interest in medicinal chemistry. Safety data indicates that, like many organic acids, it should be handled with care to avoid irritation or adverse reactions.

Formula: C₉H₁₀O₂

InChI: InChI=1S/C9H10O2/c1-7(9(10)11)8-5-3-2-4-6-8/h2-7H,1H3,(H,10,11)

InChI key: InChIKey=YPGCWEMNNLXISK-UHFFFAOYSA-N

SMILES: C(C(O)=O)(C)C1=CC=CC=C1

Synonyms:

• (RS)-2-Phenylpropanoic acid
• (RS)-2-Phenylpropionic acid
• (±)-α-Methylphenylacetic acid
• 2-Phenyl propionic acid
• 2-Phenylpropanoic acid
• 2-Phenylpropionic acid
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-2-Phenylpropionic acid
• Benzeneacetic acid, alpha-methyl-
• Benzeneacetic acid, α-methyl-
• Benzeneaceticacid,Α-Methyl
• DL-Hydratropic acid
• DL-alpha-Phenylpropionic Acid
• Hydratropic acid
• NSC 245033
• NSC 42872
• dl-PPA
• Α-Phenylpropionic Acid
• α-Methylbenzeneacetic acid

DL-2-Phenylpropionic Acid

CAS: 492-37-5

Formula: C₉H₁₀O₂

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 150.18

Ref: 3B-P0699

(+/-)-2-Phenylpropionic acid, 98%

CAS: 492-37-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₁₀O₂

Purity: 98%

Color and Shape: Clear, pale yellow, Liquid

Molecular weight: 150.18

Ref: 02-L00709

2-Phenylpropionic acid

CAS: 492-37-5

Formula: C₉H₁₀O₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 150.1745

Ref: IN-DA003PSY

2-Phenylpropionic acid

CAS: 492-37-5

Formula: C₉H₁₀O₂

Molecular weight: 150.18

Ref: 7W-GL6812

2-Phenylpropanoic acid

CAS: 492-37-5

2-Phenylpropanoic acid

Formula: C₉H₁₀O₂

Purity: 98%

Color and Shape: faint red. contains solids liquid

Molecular weight: 150.17g/mol

Ref: 54-OR2976

Loxoprofen Impurity 25

CAS: 492-37-5

Formula: C₉H₁₀O₂

Molecular weight: 150.18

Ref: 4Z-L-8948

2-Phenylpropionic acid

CAS: 492-37-5

Formula: C₉H₁₀O₂

Purity: 97%

Color and Shape: Liquid, Clear

Molecular weight: 150.177

Ref: 10-F093725

(±)-2-Phenylpropanoic Acid

CAS: 492-37-5

Applications Used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers.
References Leeman, M. et al.: Angew. Chem. Int. Ed., 47, 1287 (2008); Eur. J. Med. Chem., 45, 3564 (2010);

Formula: C₉H₁₀O₂

Color and Shape: Light Yellow Liquid

Molecular weight: 150.17

Ref: TR-P336170

2-Phenylpropionic acid

CAS: 492-37-5

2-Phenylpropionic acid is a reactive chemical that can be synthesized by an asymmetric process. It has been used in the synthesis of nonsteroidal anti-inflammatory drugs, as it inhibits the activity of cyclooxygenase and lipoxygenase enzymes. This chemical also binds to the hydroxyl group on target proteins, inhibiting their function. 2-Phenylpropionic acid is metabolized by microbial metabolism and can inhibit the activity of drug-metabolizing enzymes such as CYP3A4 and CYP2D6. It may also interact with other drugs that are processed by these enzymes, including warfarin and carbamazepine. 2-Phenylpropionic acid is a competitive inhibitor that binds to the active site of an enzyme and blocks its access to its substrate molecule. The binding of 2-phenylpropionic acid to enzyme's active site prevents the reactant from entering and reacting with the enzyme, thereby preventing a

Formula: C₉H₁₀O₂

Purity: Min. 95%

Color and Shape: Colorless Clear Liquid

Molecular weight: 150.17 g/mol

Ref: 3D-FP35013