CAS 4928-02-3
:7-Aminonitrazepam
Description:
7-Aminonitrazepam is a chemical compound belonging to the benzodiazepine class, which is characterized by its psychoactive properties. It is a derivative of nitrazepam, featuring an amino group at the 7-position of the benzodiazepine ring. This modification influences its pharmacological activity, primarily as a central nervous system depressant. The compound is known for its anxiolytic, sedative, and muscle relaxant effects, making it of interest in both clinical and research settings. In terms of physical properties, 7-Aminonitrazepam is typically a crystalline solid, and its solubility can vary depending on the solvent used. The compound's mechanism of action involves the modulation of GABA-A receptors, enhancing the inhibitory effects of the neurotransmitter gamma-aminobutyric acid (GABA). Due to its psychoactive nature, 7-Aminonitrazepam is subject to regulatory scrutiny in many countries, and its use is often limited to specific medical contexts. Safety and toxicity profiles are important considerations, as with other benzodiazepines, particularly regarding dependence and withdrawal symptoms.
Formula:C15H13N3O
InChI:InChI=1S/C15H13N3O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9,16H2,(H,18,19)
InChI key:InChIKey=OYOUQHVDCKOOAL-UHFFFAOYSA-N
SMILES:NC=1C=C2C(=NCC(=O)NC2=CC1)C3=CC=CC=C3
Synonyms:- 1,3-Dihydro-7-amino-5-phenyl-2H-1,4-benzodiazepin-2-one
- 2H-1,4-benzodiazepin-2-one, 7-amino-1,3-dihydro-5-phenyl-
- 7-Amino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 7-Aminonitrazepam
- Ro 05-3072
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Found 11 products.
7-Amino Nitrazepam
CAS:Controlled Product<p>Applications A metabolite of Nitrazepam (N490140).<br>References Randall, L.O., et al.: Biochem. Pharmacol., 8, 15 (1961),<br></p>Formula:C15H13N3OColor and Shape:Light YellowMolecular weight:251.287-Amino Nitrazepam (1mg/ml in Methanol)
CAS:Controlled ProductFormula:C15H13N3OColor and Shape:Single SolutionMolecular weight:251.287-Amino nitrazepam
CAS:Controlled Product<p>7-Amino nitrazepam is a metabolite of the benzodiazepine drug flunitrazepam. It is formed in the liver by cytochrome P450 and excreted in the urine. 7-Amino nitrazepam has been shown to have inhibitory effects on human liver and human serum. The inhibitory activity was found to be more potent than that of flunitrazepam, but less potent than that of alprazolam. 7-Amino nitrazepam was also found to inhibit rat liver microsomes, which could lead to a higher potency in vivo. This study also showed that 7-Amino nitrazepam is absorbed from the gastrointestinal tract and distributed into all tissues, including the brain, and can be detected in blood serum and urine samples.</p>Formula:C15H13N3OPurity:Min. 95%Molecular weight:251.28 g/molRef: 3D-FA17373
Discontinued product
