CAS 4928-03-4

7-Acetamidonitrazepam

Description:

7-Acetamidonitrazepam, with the CAS number 4928-03-4, is a chemical compound belonging to the benzodiazepine class, which is known for its psychoactive properties. This substance features a nitro group and an acetamido group, contributing to its pharmacological profile. It is characterized by its ability to interact with the central nervous system, primarily functioning as a sedative and anxiolytic agent. The compound exhibits a high affinity for the GABA-A receptor, enhancing the inhibitory effects of the neurotransmitter gamma-aminobutyric acid (GABA). This interaction leads to increased neuronal inhibition, resulting in calming effects. 7-Acetamidonitrazepam is typically studied for its potential therapeutic applications, but it may also pose risks of dependence and side effects, common to many benzodiazepines. Its solubility, stability, and specific reactivity can vary based on environmental conditions and formulation. As with all controlled substances, its use is regulated in many jurisdictions due to concerns regarding abuse and safety.

Formula: C₁₇H₁₅N₃O₂

InChI: InChI=1S/C17H15N3O2/c1-11(21)19-13-7-8-15-14(9-13)17(18-10-16(22)20-15)12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H,19,21)(H,20,22)

InChI key: InChIKey=JHTJXLGLYZQIGI-UHFFFAOYSA-N

SMILES: N(C(C)=O)C=1C=C2C(=NCC(=O)NC2=CC1)C3=CC=CC=C3

Synonyms:

• 1,3-Dihydro-7-acetamido-5-phenyl-2H-1,4-benzodiazepin-2-one
• 1H-1,4-Benzodiazepine, acetamide deriv.
• 2H-1,4-Benzodiazepin-2-one, 7-acetamido-1,3-dihydro-5-phenyl-
• 7-(Acetylamino)nitrazepam
• 7-Acetamido-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
• 7-Acetamidonitrazepam
• 7-Acetamino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
• 7-Acetylaminonimetazepam
• N-(2,3-Dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-7-yl)acetamide
• NSC 58777
• Ro 05-3305

7-Acetamido Nitrazepam 1.0 mg/mL in Methanol

Controlled Product

CAS: 4928-03-4

Formula: C₁₇H₁₅N₃O₂

Color and Shape: Single Solution

Molecular weight: 293.32

Ref: TR-KIT0940

7-Acetamido Nitrazepam

Controlled Product

CAS: 4928-03-4

Formula: C₁₇H₁₅N₃O₂

Color and Shape: Neat

Molecular weight: 293.32

Ref: TR-A158470

7-Acetamido nitrazepam

Controlled Product

CAS: 4928-03-4

7-Acetamido nitrazepam is a benzodiazepine derivative that is used as a hypnotic, anxiolytic and anticonvulsant. It has been shown to have a longer duration of action than diazepam, which is its parent compound. 7-Acetamido nitrazepam has been detected in the urine of geriatric patients who have taken it orally, with concentrations peaking between 1 and 2 hours after ingestion. The plasma concentration of 7-acetamido nitrazepam in Sprague Dawley rats was found to be about 3 times higher than that of triazolam, another benzodiazepine. In rat liver microsomes, 7-acetamido nitrazepam was found to be metabolized by human CYP2E1 enzymes to form N-oxides, which are then conjugated with glucuronic acid or sulphate. 7-Acetamido nitrazepam is

Formula: C₁₇H₁₅N₃O₂

Purity: Min. 95%

Molecular weight: 293.32 g/mol

Ref: 3D-FA16920

7-Acetamido Nitrazepam

CAS: 4928-03-4

Formula: C₁₇H₁₅N₃O₂

Molecular weight: 293.33

Ref: ST-EA-CP-N96006