CAS 493-48-1

Salsolidine

Description:

Salsolidine, with the CAS number 493-48-1, is an alkaloid derived from various plant sources, particularly from the Salsola genus. It is characterized by its complex bicyclic structure, which includes a piperidine ring fused to a quinoline system. This compound exhibits a range of biological activities, including potential analgesic and anti-inflammatory properties, making it of interest in pharmacological research. Salsolidine is typically found in a crystalline form and is soluble in organic solvents, but its solubility in water is limited. The compound's molecular formula reflects its nitrogen-containing structure, which is common among alkaloids. Due to its biological significance, salsolidine has been studied for its effects on the central nervous system and its potential therapeutic applications. However, like many alkaloids, it may also exhibit toxicity at certain concentrations, necessitating careful handling and further investigation into its safety profile. Overall, salsolidine represents a fascinating subject within the field of natural product chemistry and pharmacology.

Formula: C₁₂H₁₇NO₂

InChI: InChI=1S/C12H17NO2/c1-8-10-7-12(15-3)11(14-2)6-9(10)4-5-13-8/h6-8,13H,4-5H2,1-3H3/t8-/m0/s1

InChI key: InChIKey=HMYJLVDKPJHJCF-QMMMGPOBSA-N

SMILES: C[C@H]1C=2C(=CC(OC)=C(OC)C2)CCN1

Synonyms:

• (S)-(-)-Salsolidine
• (S)-Salsolidine
• Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-, (1S)-
• Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-, (S)-
• Salsolidine
• Salsolidine
• Salsolidin
• 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
• (1S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methylisoquinoline
• (S)-6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
• Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-
• Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-, (S)-
• Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-, (1S)-
• (-)-Salsolidine

(S)-Salsolidine

CAS: 493-48-1

(S)-Salsolidine is a MAO inhibitor with Ki 63μM; its R enantiomer is more effective, Ki 26μM.

Formula: C₁₂H₁₇NO₂

Color and Shape: Solid

Molecular weight: 207.27

Ref: TM-T40576