CAS 4945-47-5

Bamipine

Description:

Bamipine, with the CAS number 4945-47-5, is a chemical compound that belongs to the class of antihypertensive agents. It is primarily characterized by its ability to act as a calcium channel blocker, which helps in the relaxation of blood vessels and subsequently lowers blood pressure. The molecular structure of Bamipine includes a piperidine ring, contributing to its pharmacological properties. It is typically administered in the form of its hydrochloride salt to enhance solubility and bioavailability. Bamipine is known for its relatively low toxicity profile and is often used in clinical settings to manage hypertension. Its mechanism of action involves inhibiting the influx of calcium ions into vascular smooth muscle and cardiac cells, leading to vasodilation. Additionally, Bamipine may exhibit some sedative effects, which can be beneficial in certain therapeutic contexts. As with any medication, it is essential to consider potential side effects and interactions with other drugs when prescribing or using Bamipine.

Formula: C₁₉H₂₄N₂

InChI: InChI=1S/C19H24N2/c1-20-14-12-19(13-15-20)21(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17/h2-11,19H,12-16H2,1H3

InChI key: InChIKey=VZSXTYKGYWISGQ-UHFFFAOYSA-N

SMILES: N(CC1=CC=CC=C1)(C2CCN(C)CC2)C3=CC=CC=C3

Synonyms:

• 1-Methyl-N-phenyl-N-(phenylmethyl)-4-piperidinamine
• 4-(N-Benzylanilino)-1-methylpiperidine
• 4-Piperidinamine, 1-methyl-N-phenyl-N-(phenylmethyl)-
• Bamipin
• N-Phenyl-N-benzyl-4-amino-1-methylpiperidine
• N-benzyl-N-(1-methyl-4-piperidyl)aniline
• Piperidine, 4-(N-benzylanilino)-1-methyl-
• Soventol
• Taumidrine
• Bamipine

N-BENZYL-1-METHYL-N-PHENYLPIPERIDIN-4-AMINE

CAS: 4945-47-5

Formula: C₁₉H₂₄N₂

Purity: 95.0%

Molecular weight: 280.415

Ref: 10-F474623

Bamipine

Controlled Product

CAS: 4945-47-5

Formula: C₁₉H₂₄N₂

Color and Shape: Neat

Molecular weight: 280.407

Ref: TR-B117925

Bamipine-d5

Controlled Product

CAS: 4945-47-5

Applications Bamipine is an antihistamine that has anticholinergic properties. It is also a reagent for dopamine D3 receptor ligands based on scaffolds of biogenic amine GPCR (G protein-coupled receptor) ligands.
References Sasse, B.C., et al.: Bioorg. Med. Chem., 15, 7258 (2007)

Formula: C₁₉D₅H₁₉N₂

Color and Shape: Neat

Molecular weight: 285.438

Ref: TR-B117927

Bamipine

CAS: 4945-47-5

Bamipine is a potent antagonist of the histamine H1-receptor (histamine H1-receptor). It exhibits moderate activity against Mycobacterium tuberculosis and possesses mild anti-sedative effects.

Formula: C₁₉H₂₄N₂

Molecular weight: 280.4073

Ref: TM-T214711