CAS 4947-89-1

N-(3-Chlorophenyl)thiourea

Description:

N-(3-Chlorophenyl)thiourea is an organic compound characterized by the presence of a thiourea functional group attached to a chlorinated phenyl ring. Its molecular structure features a thiourea moiety, which consists of a carbon atom double-bonded to a sulfur atom and single-bonded to an amine group, along with a phenyl ring substituted with a chlorine atom at the meta position. This compound typically appears as a white to off-white solid and is soluble in polar organic solvents. N-(3-Chlorophenyl)thiourea is of interest in various fields, including medicinal chemistry and agrochemicals, due to its potential biological activities, such as antifungal and herbicidal properties. The presence of the chlorine atom can influence its reactivity and interaction with biological targets. As with many thiourea derivatives, it is essential to handle this compound with care, as thioureas can exhibit toxicity and may pose environmental hazards. Proper safety protocols should be followed when working with this substance in laboratory settings.

Formula: C₇H₇ClN₂S

InChI: InChI=1S/C7H7ClN2S/c8-5-2-1-3-6(4-5)10-7(9)11/h1-4H,(H3,9,10,11)

InChI key: InChIKey=LSYZRUOXXOTVAV-UHFFFAOYSA-N

SMILES: N(C(N)=S)C1=CC(Cl)=CC=C1

Synonyms:

• (m-Chlorophenyl)thiourea
• 1-(3-Chlorophenyl)Thiourea
• 1-(m-Chlorophenyl)thiourea
• 3-(Chlorophenyl)thiourea
• Brn 2090370
• N-(3-Chlorophenyl)thiourea
• Nsc 164965
• Thiourea, (3-chlorophenyl)-
• Thiourea, (3-chlorophenyl)- (9CI)
• Thiourea, N-(3-chlorophenyl)-
• Urea, 1-(m-chlorophenyl)-2-thio-

(3-Chlorophenyl)thiourea

CAS: 4947-89-1

Formula: C₇H₇ClN₂S

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 186.66

Ref: 3B-C3168

1-(3-Chlorophenyl)-2-thiourea

CAS: 4947-89-1

Formula: C₇H₇ClN₂S

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 186.66

Ref: 10-F010662

3-Chlorophenylthiourea

CAS: 4947-89-1

Formula: C₇H₇ClN₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 186.6619

Ref: IN-DA0033OH

1-(3-Chlorophenyl) thiourea

CAS: 4947-89-1

1-(3-Chlorophenyl) thiourea is a curcumin analog that has been shown to inhibit the epidermal growth factor (EGF) receptor. It is synthesized from 1,2-dichlorobenzene and urea in a two-step process. The anhydrous potassium carbonate is first converted to the potassium salt with an acid chloride. The second step is the reaction of this salt with urea in the presence of excess anhydrous potassium carbonate. This product has been shown to be effective against cancer cells and may be used as a potential anticancer agent for treatment of skin cancer. 1-(3-Chlorophenyl) thiourea inhibits EGF receptor by binding to it and preventing its activation, which prevents cell proliferation and reduces tumor size.

Purity: Min. 95%

Ref: 3D-FC12603