CAS 494844-07-4

8-Chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydro-N-1-piperidinylbenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide

Description:

8-Chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydro-N-1-piperidinylbenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide, with CAS number 494844-07-4, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple aromatic rings and a piperidine moiety. This compound features a chloro substituent and a dichlorophenyl group, contributing to its potential biological activity. It is primarily studied for its pharmacological properties, particularly in the context of its role as a potential therapeutic agent. The presence of the carboxamide functional group suggests that it may engage in hydrogen bonding, influencing its solubility and interaction with biological targets. The compound's intricate structure may also confer specificity in its mechanism of action, making it a subject of interest in medicinal chemistry and drug development. As with many such compounds, understanding its stability, reactivity, and biological interactions is crucial for evaluating its potential applications in pharmaceuticals.

Formula: C₂₄H₂₃Cl₃N₄O

InChI: InChI=1S/C24H23Cl3N4O/c25-16-7-9-18-15(13-16)5-4-6-19-22(24(32)29-30-11-2-1-3-12-30)28-31(23(18)19)21-10-8-17(26)14-20(21)27/h7-10,13-14H,1-6,11-12H2,(H,29,32)

InChI key: InChIKey=NCXBPZJQQSNIRA-UHFFFAOYSA-N

SMILES: C(NN1CCCCC1)(=O)C=2C3=C(N(N2)C4=C(Cl)C=C(Cl)C=C4)C=5C(CCC3)=CC(Cl)=CC5

Synonyms:

• Benzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide, 8-chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydro-N-1-piperidinyl-
• 8-Chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydro-N-1-piperidinylbenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide
• N-(Piperidin-1-yl)-8-chloro-1-(2′,4′-dichlorophenyl)-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide
• NESS 0327

N-PIPERIDINYL-[8-CHLORO-1-(2,4-DICHLOROPHENYL)-1,4,5,6-TETRAHYDROBENZO-[6,7]CYCLOHEPTAL[1,2-C]PYRAZOLE-3-CARBOXAMIDE

CAS: 494844-07-4

Formula: C₂₄H₂₃Cl₃N₄O

Purity: 98%

Molecular weight: 489.8246

Ref: IN-DA00DAAU

NESS 0327

CAS: 494844-07-4

NESS 0327

Purity: ≥98%

Molecular weight: 489.82g/mol

Ref: 54-BUP11567

NESS 0327

CAS: 494844-07-4

NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.

Formula: C₂₄H₂₃Cl₃N₄O

Purity: 99.78%

Color and Shape: Solid

Molecular weight: 489.82

Ref: TM-T22114

NESS-0327

Controlled Product

CAS: 494844-07-4

NESS-0327 is a ligand that binds to the CB2 receptor and inhibits the production of inflammatory cytokines. It has been shown to be effective in mouse models of autoimmune diseases, metabolic disorders, and oxidative stress. NESS-0327 has been shown to have anti-inflammatory properties by inhibiting acetylcholinesterase activity and modulating energy metabolism. This drug also has an effect on intracellular calcium concentration and fatty acid metabolism. NESS-0327 is a pyrazole derivative that has been shown to inhibit polymerase chain reaction (PCR) uptake in fatty acid cells.

Purity: Min. 95%

Ref: 3D-CN175169

NESS 0327

Controlled Product

CAS: 494844-07-4

Formula: C₂₄H₂₃Cl₃N₄O

Color and Shape: Neat

Molecular weight: 489.825

Ref: TR-N385708