CAS 495-79-4

Coumarinic acid

Description:

Coumarinic acid, with the CAS number 495-79-4, is a naturally occurring compound belonging to the class of coumarins, which are aromatic compounds characterized by a benzopyrone structure. It typically appears as a white to pale yellow crystalline solid and is soluble in organic solvents like ethanol and acetone, but has limited solubility in water. The compound exhibits a range of biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties, making it of interest in pharmaceutical and cosmetic applications. Coumarinic acid can be synthesized through various methods, including the condensation of phenolic compounds with α,β-unsaturated carbonyl compounds. Its structure features a lactone ring, which contributes to its reactivity and interaction with biological systems. Additionally, coumarinic acid can serve as a precursor for the synthesis of other coumarin derivatives, which are widely studied for their potential therapeutic effects. Overall, coumarinic acid is a versatile compound with significant implications in medicinal chemistry and natural product research.

Formula: C₉H₈O₃

InChI: InChI=1S/C9H8O3/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6,10H,(H,11,12)/b6-5-

InChI key: InChIKey=PMOWTIHVNWZYFI-WAYWQWQTSA-N

SMILES: C(=C\C(O)=O)\C1=C(O)C=CC=C1

Synonyms:

• Coumarinic acid
• Cinnamic acid, o-hydroxy-, (Z)-
• 2-Propenoic acid, 3-(2-hydroxyphenyl)-, (2Z)-
• (2Z)-3-(2-Hydroxyphenyl)-2-propenoic acid
• 2-Propenoic acid, 3-(2-hydroxyphenyl)-, (Z)-

Coumarinic acid

CAS: 495-79-4

Coumarinic acid serves as a brain-penetrating inhibitor of AChE (acetylcholinesterase) and β-amyloid, with applications in anti-Alzheimer's drug research [1].

Formula: C₉H₈O₃

Color and Shape: Solid

Molecular weight: 164.16

Ref: TM-T79968