CAS 495-85-2
:(+)-Methysticin
Description:
(+)-Methysticin is a naturally occurring compound classified as a flavonoid, specifically a methysticin derivative, primarily found in the plant species *Piper methysticum*, commonly known as kava. This compound is known for its psychoactive properties and has been traditionally used in various cultures for its calming and anxiolytic effects. Chemically, it features a complex structure that includes a chromone backbone, contributing to its biological activity. (+)-Methysticin exhibits antioxidant properties and has been studied for its potential therapeutic effects, including anti-inflammatory and neuroprotective activities. The compound is typically characterized by its solubility in organic solvents and limited solubility in water. Its pharmacological profile suggests that it may interact with neurotransmitter systems, although further research is necessary to fully elucidate its mechanisms of action and potential health benefits. As with many natural products, the safety and efficacy of (+)-Methysticin in therapeutic applications require careful consideration and further investigation.
Formula:C15H14O5
InChI:InChI=1S/C15H14O5/c1-17-12-7-11(20-15(16)8-12)4-2-10-3-5-13-14(6-10)19-9-18-13/h2-6,8,11H,7,9H2,1H3/b4-2+/t11-/m0/s1
InChI key:InChIKey=GTEXBOVBADJOQH-FWEMWIAWSA-N
SMILES:C(=C/[C@H]1CC(OC)=CC(=O)O1)\C=2C=C3C(=CC2)OCO3
Synonyms:- (+)-Methysticin
- (6R)-6-[(1E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one
- (6R)-6-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
- (6R)-6-[(E)-2-(1,3-benzodioxol-5-yl)vinyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
- 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[3,4-(methylenedioxy)styryl]-, (R)-
- 2H-Pyran-2-one, 6-[(1E)-2-(1,3-benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-, (6R)-
- 2H-Pyran-2-one, 6-[2-(1,3-benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-, [R-(E)]-
- 2H-pyran-2-one, 6-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-, (6R)-
- 4-Methoxy-6-[b-(3',4'-methylenedioxyphenyl)vinyl]-5,6-dihydro-a-pyrone
- 5-Hydroxy-3-methoxy-7-[3,4-(methylenedioxy)phenyl]-2,6-heptadienoic Acid d-Lactone
- 6-(3',4'-Methylenedioxystyryl)-4-methoxy-5,6-dihydro-2H-pyran-2-one
- Kavahin
- Kavatin
- Methylsticin
- NSC 112158
- [R-(E)]-6-[2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one
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Found 9 products.
Methylsticin
CAS:Methysticin, a kavalactone from kava roots, inhibits osteoclasts, NF-χB, stimulates Nrf2, reduces Na+ channel peaks, and hinders fungal growth.Formula:C15H14O5Purity:99.27% - 99.37%Color and Shape:White PowderMolecular weight:274.27Methysticin
CAS:LactoneFormula:C15H14O5Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:274.27Kavatin
CAS:Controlled Product<p>Applications A lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. One of the active components of the intoxicating beverage Kava from the Pacific Islands.<br>References Keledjian, J., et al.: J. Pharm. Sci., 77, 1003 (1988), Clouatre, D., et al.: Toxicol. Lett., 150, 85 (2004), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Clayton, N., et al.: Exp. Toxicol. Pathol., 58, 223 (2007),<br></p>Formula:C15H14O5Color and Shape:NeatMolecular weight:274.27Methysticin
CAS:Methysticin is one of the major kavalactones found in the roots of the kava plant, which is scientifically known as *Piper methysticum*. This compound is derived from the rhizomes of the South Pacific plant, where it exists alongside other kavalactones that collectively contribute to the plant’s bioactive profile. Methysticin's primary mode of action is believed to involve modulation of neurotransmitter systems, particularly through interactions with GABAergic pathways, leading to its anxiolytic and sedative effects.Formula:C15H14O5Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:274.27 g/mol
