CAS 49562-28-9

Fenofibrate

Description:

Fenofibrate is a pharmaceutical compound primarily used as a lipid-regulating agent to manage dyslipidemia and reduce cardiovascular risk. It belongs to the class of fibrates, which are derivatives of fibric acid. The chemical formula of fenofibrate is C20H21O4S, and it features a phenolic structure with a carboxylic acid group and a thioether linkage. Fenofibrate acts by activating peroxisome proliferator-activated receptor alpha (PPAR-α), which enhances the oxidation of fatty acids and decreases triglyceride levels while increasing high-density lipoprotein (HDL) cholesterol. It is typically administered orally and is well-absorbed in the gastrointestinal tract, with its bioavailability influenced by food intake. Fenofibrate is generally well-tolerated, but potential side effects may include gastrointestinal disturbances, liver enzyme elevations, and muscle-related issues. Its therapeutic efficacy is often evaluated in conjunction with lifestyle modifications, such as diet and exercise, to achieve optimal lipid control. Fenofibrate is commonly prescribed in various formulations, including tablets and capsules, and is often used in combination with statins for enhanced lipid-lowering effects.

Formula: C₂₀H₂₁ClO₄

InChI: InChI=1/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3

InChI key: InChIKey=YMTINGFKWWXKFG-UHFFFAOYSA-N

SMILES: C(=O)(C1=CC=C(OC(C(OC(C)C)=O)(C)C)C=C1)C2=CC=C(Cl)C=C2

Synonyms:

• 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid 1-methylethyl ester
• Ankebin
• Antara
• Clorofibrate
• Elasterin
• Fenobrate
• Fenofibrat
• Fenofibrate
• Fenofibrato
• Fenogal
• Fenorate
• Fenotard
• Isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
• Isopropyl 2-[p-(p-chlorobenzoyl)phenoxy]-2-methylpropionate
• Lf 178
• Lipanthyl
• Lipanthylnano
• Lipantil
• Lipicard
• Lipidil
• Lipidil Supra
• Lipirex
• Lipivim
• Lipoclar
• Lipofene
• Liposit
• Lipsin
• MeltDose
• Nolipax
• Nsc 281319
• Procetofen
• Procetofene
• Procetoken
• Protolipan
• Secalip
• TriCor
• Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester
• sedufen
• proctofene
• 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoic acid isopropyl ester
• isopropyl2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate
• lipifen
• Fenofibrate (200 mg)
• 2-[p-(p-Chlorobenzoyl)phenoxy]-2-methylpropionic acid isopropyl ester
• ethyl 2-[4-(4-chlorophenyl)carbonylphenoxy]-2-methyl-propanoate
• Fenofibrate API
• Fenofibrate COS
• Lipantyl
• 2-[4-[p-Chlorobenzoyl]]-2-methylpropionic acid isopropyl ester
• 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-propanoicaci1-methylethylester
• isopropyl(4’-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate
• Fenofibrite
• lipidax
• Fenofibrate,2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester
• Fenofibrate, >=99%
• 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic Acid Isopropyl Ester
• LIPYDIL
• 2-[4-[(4-chlorophenyl)-oxomethyl]phenoxy]-2-methylpropanoic acid ethyl ester
• 2-[4-(4-CHLOROBENZOYL)PHENOXYL-2-METHYLPROPANOIC ACID 1-METHYLETHYL ESTER
• 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propionic acid isopropyl ester
• LABOTEST-BB LT00771982
• propan-2-yl 2-[4-(4-chlorophenyl)carbonylphenoxy]-2-methyl-propanoate
• propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate
• Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-, ethyl ester
• 2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYL-PROPANOIC ACID, 1-METHYLETHYL ESTER

Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate

CAS: 49562-28-9

Formula: C₂₀H₂₁ClO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 360.83

Ref: 10-F223141

Fenofibrate RS

CAS: 49562-28-9

Color and Shape: White Solid Crystalline Powder

Ref: 2K-1127900021