CAS 4959-17-5
:7-Aminoclonazepam
Description:
7-Aminoclonazepam is a chemical compound that belongs to the benzodiazepine class of drugs, which are known for their psychoactive properties. It is a derivative of clonazepam, characterized by the presence of an amino group at the 7-position of the benzodiazepine ring. This modification enhances its pharmacological profile, contributing to its anxiolytic, anticonvulsant, and muscle relaxant effects. The compound is typically a white to off-white crystalline powder and is soluble in organic solvents like ethanol and dimethyl sulfoxide, but has limited solubility in water. Its molecular structure includes a fused benzene and diazepine ring, which is essential for its biological activity. 7-Aminoclonazepam is primarily studied for its potential therapeutic applications and is of interest in pharmacological research, particularly in understanding the mechanisms of action of benzodiazepines. However, it is important to note that the use of such compounds should be approached with caution due to their potential for dependence and side effects.
Formula:C15H12ClN3O
InChI:InChI=1S/C15H12ClN3O/c16-12-4-2-1-3-10(12)15-11-7-9(17)5-6-13(11)19-14(20)8-18-15/h1-7H,8,17H2,(H,19,20)
InChI key:InChIKey=HEFRPWRJTGLSSV-UHFFFAOYSA-N
SMILES:NC=1C=C2C(=NCC(=O)NC2=CC1)C3=C(Cl)C=CC=C3
Synonyms:- 2H-1,4-Benzodiazepin-2-one, 7-amino-5-(o-chlorophenyl)-1,3-dihydro-
- 2H-1,4-benzodiazepin-2-one, 7-amino-5-(2-chlorophenyl)-1,3-dihydro-
- 7-Amino-5-(o-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- 7-Aminoclonazepam
- Aminoclonazepam
- Chloraminazepam
- Ro 5-4619
- 7-Amino-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
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Found 9 products.
7-Amino Clonazepam
CAS:Controlled Product<p>Applications The major metabolite of Clonazepam (C587080).<br>References Clark, D., et al.: Drugs, 29, 342 (1985), Colmenero, J., et al.: Antimicrob. Agents Chemother., 38, 2798 (1994), Grant, D., et al.: Pharmacology, 61, 204 (2000), Negrusz, A., et al.: Anal. Bioanal. Chem., 376, 1198 (2003),<br></p>Formula:C15H12ClN3OColor and Shape:YellowMolecular weight:285.737-Amino clonazepam
CAS:Controlled Product<p>7-Amino clonazepam is a metabolite of clonazepam. It has been detected in the urine of psychiatric patients and can be used as a marker for the diagnosis and monitoring of clonazepam abuse. The chromatographic method for detection of 7-aminoclonazepam is based on the analysis of human serum samples. The sample preparation is done by liquid/liquid extraction with methanol and concentrated under vacuum to remove water, which is then evaporated under high vacuum. Chromatography is carried out using an analytical column and eluted with a mobile phase consisting of acetonitrile/water (7:3). Detection time ranges from 2 to 3 hours.</p>Formula:C15H12ClN3OPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:285.73 g/mol7-Amino Clonazepam-13C2,15N
CAS:Controlled Product<p>Applications 7-Amino Clonazepam-13C2, 15N, is the labeled analogue of 7-Amino Clonazepam (A603610), major metabolite of Clonazepam (C587080).<br>References Clark, D., et al.: Drugs, 29, 342 (1985), Colmenero, J., et al.: Antimicrob. Agents Chemother., 38, 2798 (1994), Grant, D., et al.: Pharmacology, 61, 204 (2000), Negrusz, A., et al.: Anal. Bioanal. Chem., 376, 1198 (2003),<br></p>Formula:C2C13H12Cl15NN2OColor and Shape:NeatMolecular weight:288.707
